Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963287 | 0.77 | CES2 (0.48) | SRCCYP2D6LMNAMAPK1KCNQ2 | |
| SCHEMBL585336 | 0.77 | CTSD (0.54) | HPGDSRCCYP2D6LMNAMAPK1 | |
| SCHEMBL9394507 | 0.77 | SRC (0.50) | SRCCYP2D6LMNAMAPK1CTSD | |
| SCHEMBL28232476 | 0.77 | SRC (0.56) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL28232530 | 0.77 | SRC (0.56) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL241909 | 0.77 | SRC (0.56) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL3877254 | 0.76 | KEAP1 (0.43) | HPGDSRCCYP2D6LMNAMAPK1 | |
| SCHEMBL1562538 | 0.76 | HPGD (0.70) | HPGDSRCCYP2D6LMNAMAPK1 | |
| SCHEMBL2971437 | 0.76 | HPGD (0.70) | HPGDSRCCYP2D6LMNAMAPK1 | |
| SCHEMBL10967434 | 0.76 | CES2 (0.46) | SRCCYP2D6LMNAMAPK1KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611837-B1 | METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-03-15 | — | — | EP | disclosed |
| EP-2478021-B1 | Nitrile rubbers and production of same in organic solvents | LANXESS DEUTSCHLAND GMBH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2810956-A1 | Nitrile rubbers coupled with bisdihydropyrazole groups, production and use of the same | LANXESS Deutschland GmbH (DE) | 2014-12-10 | — | — | EP | disclosed |
| EP-2810957-A1 | Nitrile rubbers coupled with bisdihydropyrazole groups, production and use of the same | LANXESS Deutschland GmbH (DE) | 2014-12-10 | — | — | EP | disclosed |
| EP-2798001-A1 | METHOD FOR PRODUCING PURIFIED NITRILE RUBBERS | LANXESS Deutschland GmbH (DE) | 2014-11-05 | — | — | EP | disclosed |
| EP-2739661-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS Deutschland GmbH (DE) | 2014-06-11 | — | — | EP | disclosed |
| EP-2623518-A1 | Nitrile rubbers coupled with bistriazolyl groups, production and use of same | Lanxess Deutschland GmbH (DE) | 2013-08-07 | — | — | EP | disclosed |
| EP-2611843-A1 | METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | Lanxess Deutschland GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| EP-2611837-A1 | METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | Lanxess Deutschland GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| EP-2611836-A1 | RUBBER BLENDS CONSISTING OF DIFFERENT NITRILE RUBBERS | Lanxess Deutschland GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| EP-2478021-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | Lanxess Deutschland GmbH (DE) | 2012-07-25 | — | — | EP | disclosed |
| WO-2012028501-A1 | METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012028506-A1 | RUBBER BLENDS CONSISTING OF DIFFERENT NITRILE RUBBERS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012028503-A1 | METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
| EP-2423235-A1 | Method for producing nitrile rubbers in organic solvents | LANXESS Deutschland GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-2423238-A1 | Method for producing nitrile rubbers in organic solvents | LANXESS Deutschland GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-2423234-A1 | Rubber blends from different nitrile rubbers | LANXESS Deutschland GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-2385074-A1 | Nitrile rubbers and production of same in organic solvents | LANXESS Deutschland GmbH (DE) | 2011-11-09 | — | — | EP | disclosed |
| US-8038675-B2 | Apparatus for arrhythmia treatment based on spectral mapping during sinus rhythm | ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2011032832-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2011-03-24 | — | — | WO | disclosed |