SCHEMBL1628296

SCHEMBL1628296

Oc1ccnn1Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 3/20 0.50
CYP19A1 P11511 3/20 0.50
RECQL P46063 1/20 0.46
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
TSHR P16473 1/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
KDM4E B2RXH2 1/20 0.43
PKM P14618 1/20 0.42
SLC9A1 P19634 1/20 0.42
GRM2 Q14416 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ESR1 P03372 1/20 0.41
USP7 Q93009 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14722888 0.78 NPBWR1 (0.49) P2RX7CYP19A1RECQLALDH1A1HPGD
SCHEMBL4361625 0.78 P2RX7 (0.56) P2RX7CYP19A1RECQLALDH1A1HPGD
SCHEMBL21547789 0.77 P2RX7 (0.47) P2RX7CYP19A1RECQLALDH1A1HPGD
SCHEMBL20745582 0.77 NPBWR1 (0.51) CYP19A1ALDH1A1ALOX15KDM4ESMN1; SMN2
SCHEMBL4365345 0.76 TSHR (0.56) P2RX7CYP19A1RECQLALDH1A1HPGD
SCHEMBL3607562 0.76 CYP19A1 (0.50) P2RX7CYP19A1RECQLALDH1A1HPGD
SCHEMBL568868 0.76 KDM4E (0.72) P2RX7CYP19A1RECQLALDH1A1HPGD
SCHEMBL15675375 0.76 CYP19A1 (0.50) P2RX7CYP19A1RECQLALDH1A1HPGD
SCHEMBL15711585 0.76 P2RX7 (0.46) P2RX7CYP19A1RECQLALDH1A1HPGD
SCHEMBL27676261 0.76 P2RX7 (0.50) P2RX7CYP19A1RECQLALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4669612-B2 2011-04-13 JP claimed
US-20030109717-A1 Preparation of substituted hydroxypyrazoles GOTZ NORBERT (DE) 2003-06-12 US claimed
JP-2002529454-A 2002-09-10 JP claimed
EP-1127050-A1 METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 2001-08-29 EP claimed
WO-2000027821-A1 METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO claimed
EP-1127050-B1 METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES BASF SE (DE) 2010-08-25 EP disclosed
EP-1127050-B1 METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES BASF SE (DE) 2010-08-25 EP disclosed
US-7614145-B2 Method for manufacturing multilayer circuit board and resin base material ZEON CORPORATION (JP) 2009-11-10 US disclosed
CN-100496195-C Mulitilayer circuit board, resin base material, and its production method ZEON CORP (JP) 2009-06-03 CN disclosed
US-20080217617-A1 Thin Film Transistor, Wiring Board and Methods of Manufacturing the Same ZEON CORPORATION (JP) 2008-09-11 US disclosed
CN-100383278-C Partial plating method, partially-plated resin base, method for manufacturing multilayer circuit board ZEON CORP (JP) 2008-04-23 CN disclosed
US-20050153059-A1 Partial plating method, partially-plated resin base, method for manufacturing multilayered circuit board ZEON CORPORATION (JP) 2005-07-14 US disclosed
CN-1639384-A Partial plating method, partially-plated resin base, method for manufacturing multilayer circuit board ZEON CORP (JP) 2005-07-13 CN disclosed
US-20040237295-A1 Multilayer circuit board and resin base material, and its production method ZEON CORPORATION (JP) 2004-12-02 US disclosed
CN-1552174-A Mulitilayer circuit board, resin base material, and its production method �ձ�������ʽ���� 2004-12-01 CN disclosed
US-6600071-B2 Starting materials or intermediates and the cyclization of these under suitable reaction conditions to give compounds of the formula I. The intermediates of the formula II are novel. for argrochemicals BASF AKTIENGESELLSCHAFT (DE) 2003-07-29 US disclosed
US-20030109717-A1 Preparation of substituted hydroxypyrazoles GOTZ NORBERT (DE) 2003-06-12 US disclosed
US-6472538-B1 HIGH YIELD COUPLING, HYDROGENATION AND CYCLIZATION TO FORM CHEMICAL INTERMEDIATES FOR HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2002-10-29 US disclosed
EP-1127050-A1 METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 2001-08-29 EP disclosed
WO-2000027821-A1 METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109717-A1 Preparation of substituted hydroxypyrazoles CYC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS P2RX7 3547/4885CYP19A1 542/4885RECQL 266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.