Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CFTR | P13569 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Phthalate SCHEMBL790124 | 0.85 | TSHR (0.74) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL29500970 | 0.85 | TSHR (0.74) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL29669976 | 0.85 | TSHR (0.74) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL34630 | 0.85 | TSHR (0.74) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL28376050 | 0.83 | TSHR (0.71) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL30278536 | 0.83 | TSHR (0.71) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL10602130 | 0.83 | TSHR (0.71) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL27488189 | 0.83 | TSHR (0.71) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL27486580 | 0.83 | TSHR (0.71) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL27342491 | 0.83 | TSHR (0.71) | TSHRLMNAHSD17B10ALDH1A1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465869-B1 | MODULATORS OF LXR | EXELIXIS PATENT CO LLC (US) | 2013-05-15 | — | — | EP | claimed |
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | claimed |
| US-7547749-B2 | Triazine compounds, polymers comprising triazine structural units, and method | SABIC INNOVATIVE PLATICS IP B.V. (NL) | 2009-06-16 | — | — | US | claimed |
| US-RE40697-E1 | Method for making an aromatic polycarbonate | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-04-07 | — | — | US | claimed |
| CN-100406238-C | Process for producing aromatic polycarbonate | GEN ELECTRIC (US) | 2008-07-30 | — | — | CN | claimed |
| US-20080097040-A1 | TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2008-04-24 | — | — | US | claimed |
| CN-1286879-C | Method of making block copolymers by solid state polymerization | GEN ELECTRIC (US) | 2006-11-29 | — | — | CN | claimed |
| EP-1444288-B1 | METHOD OF MAKING BLOCK COPOLYMERS BY SOLID STATE POLYMERIZATION | GEN ELECTRIC (US) | 2006-06-07 | — | — | EP | claimed |
| EP-1465869-A4 | MODULATORS OF LXR | X CEPTOR THERAPEUTICS INC (US) | 2005-12-28 | — | — | EP | claimed |
| JP-2005536450-A | — | — | 2005-12-02 | — | — | JP | claimed |
| US-20030139529-A1 | Method of making block copolymers by solid state polymerization | GENERAL ELECTRIC COMPANY | 2003-07-24 | — | — | US | claimed |
| WO-2003059884-A1 | MODULATORS OF LXR | X-CEPTOR THERAPEUTICS, INC. (US) | 2003-07-24 | — | — | WO | claimed |
| US-20030130279-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2003-07-10 | — | — | US | claimed |
| WO-2003044009-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2003-05-30 | — | — | WO | claimed |
| WO-2003040208-A1 | METHOD OF MAKING BLOCK COPOLYMERS BY SOLID STATE POLYMERIZATION | GENERAL ELECTRIC COMPANY (US) | 2003-05-15 | — | — | WO | claimed |
| US-20030078347-A1 | Triazine compounds, polymers comprising triazine structural units, and method | GENERAL ELECTRIC COMPANY | 2003-04-24 | — | — | US | claimed |
| WO-2003024939-A2 | TRIAZINE COMPOUNDS POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2003-03-27 | — | — | WO | claimed |
| EP-0177740-B1 | ACYLATED SACCHARINE DERIVATIVES | BAYER AG (DE) | 1988-09-28 | — | — | EP | claimed |
| US-4713389-A | Fungicidally and bactericidally active acylated saccharin derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | claimed |
| EP-0177740-A1 | Acylated saccharine derivatives | BAYER AG (DE) | 1986-04-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130279-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD17B1, HSD3B1 | TSHR 4127/4885LMNA 1976/4885HSD17B10 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.