SCHEMBL16285652

SCHEMBL16285652

CCC(C)(C(=O)O)C(F)(F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.41
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15185179 0.86 THRB (0.33) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL800011 0.85 ALDH1A1 (0.36) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL12857950 0.85 THRB (0.32) THRB
SCHEMBL13466017 0.85 THRB (0.32) THRB
SCHEMBL9154668 0.79 TSHR (0.44) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL13127643 0.74 CYP4F2 (0.38) THRBTSHRALDH1A1HIF1AMEN1
SCHEMBL284018 0.74 TSHR (0.40) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL497469 0.73 THRB (0.42) THRBALDH1A1MEN1CYP1A2KMT2A
SCHEMBL9710097 0.72 TSHR (0.38) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL28727403 0.72 TSHR (0.38) THRBTSHRALDH1A1CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9140983-B2 Resist composition and method for forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2015-09-22 US disclosed
US-20140363772-A1 RESIST COMPOSITION AND METHOD FOR FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2014-12-11 US disclosed