Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16285787 | 0.82 | CYP1A2 (0.36) | CPB2CYP1A2 | |
| SCHEMBL16285804 | 0.80 | GSR (0.34) | CPB2CYP1A2ALDH1A1 | |
| SCHEMBL16278958 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL16278956 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL21577901 | 0.77 | GSR (0.33) | CPB2ALDH1A1 | |
| SCHEMBL11880670 | 0.77 | GSR (0.33) | CPB2ALDH1A1 | |
| SCHEMBL16278935 | 0.77 | GSR (0.33) | CPB2ALDH1A1 | |
| SCHEMBL16285771 | 0.77 | CYP1A2 (0.41) | CPB2CYP1A2 | |
| SCHEMBL16285777 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL16285772 | 0.73 | GSR (0.39) | CPB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371274-B2 | Compound having read-through activity | THE UNIVERSITY OF TOKYO (JP) | 2016-06-21 | — | — | US | disclosed |
| US-9371274-B2 | Compound having read-through activity | THE UNIVERSITY OF TOKYO (JP) | 2016-06-21 | — | — | US | disclosed |
| US-20140364642-A1 | COMPOUND HAVING READ-THROUGH ACTIVITY | THE UNIVERSITY OF TOKYO (JP) | 2014-12-11 | — | — | US | disclosed |
| US-20140364642-A1 | COMPOUND HAVING READ-THROUGH ACTIVITY | THE UNIVERSITY OF TOKYO (JP) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364642-A1 | COMPOUND HAVING READ-THROUGH ACTIVITY | UPF1, NUDT21, GBA2 | CPB2 2519/4885CYP1A2 2177/4885ALDH1A1 3424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.