SCHEMBL21577901

SCHEMBL21577901

CN(CC(=O)O)NC(=O)C[C@H](N)CCCN

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ENPEP Q07075 3/20 0.31
F2 P00734 2/20 0.31
CPB2 Q96IY4 1/20 0.31
BHMT Q93088 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11880670 1.00 GSR (0.33) GSRALDH1A1ENPEPF2CPB2
SCHEMBL16278935 1.00 GSR (0.33) GSRALDH1A1ENPEPF2CPB2
SCHEMBL16285772 0.95 GSR (0.39) GSRALDH1A1ENPEPF2CPB2
SCHEMBL16279005 0.91 GABRR1 (0.32) BHMT
SCHEMBL16279002 0.91 GABRR1 (0.32) BHMT
SCHEMBL16285804 0.84 GSR (0.34) GSRALDH1A1ENPEPCPB2
SCHEMBL16285773 0.84 KDM7A (0.32) BHMT
SCHEMBL22005470 0.84 RNPEP (0.34) F2CPB2
SCHEMBL16278956 0.82 ALDH1A1 (0.33) GSRALDH1A1
SCHEMBL16278958 0.82 ALDH1A1 (0.33) GSRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190350908-A1 METHODS FOR INDUCING AN IMMUNE RESPONSE BY PROMOTING PREMATURE TERMINATION CODON READ-THROUGH MOONSHOT PHARMA LLC 2019-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190350908-A1 METHODS FOR INDUCING AN IMMUNE RESPONSE BY PROMOTING PREMATURE TERMINATION CODON READ-THROUGH UPF1, RNGTT, NSUN2 GSR 4569/4885ALDH1A1 4854/4885ENPEP 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.