⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20362237 | 0.84 | — | — | |
| SCHEMBL1395513 | 0.82 | CES2 (0.39) | — | |
| SCHEMBL28059469 | 0.80 | DNM1 (0.42) | — | |
| SCHEMBL31079440 | 0.80 | DNM1 (0.42) | — | |
| SCHEMBL28849335 | 0.80 | DNM1 (0.42) | — | |
| SCHEMBL18641846 | 0.80 | DNM1 (0.42) | — | |
| SCHEMBL29112735 | 0.80 | DNM1 (0.42) | — | |
| SCHEMBL31079557 | 0.80 | DNM1 (0.42) | — | |
| SCHEMBL10778511 | 0.79 | CA12 (0.36) | — | |
| SCHEMBL1512269 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029146-A1 | SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE | UNIVERSITY OF WASHINGTON (US) | 2016-02-25 | — | — | WO | claimed |
| JP-4668901-B2 | — | — | 2011-04-13 | — | — | JP | claimed |
| JP-2006527217-A | — | — | 2006-11-30 | — | — | JP | claimed |
| EP-1633745-A1 | AROYL SEMICARBAZIDE DERIVATIVES AGAINST THROMBOEMBOLIC DISEASES | MERCK PATENT GmbH (DE) | 2006-03-15 | — | — | EP | claimed |
| WO-2004108718-A1 | AROYL SEMICARBAZIDE DERIVATIVES AGAINST THROMBOEMBOLIC DISEASES | MERCK PATENT GMBH (DE) | 2004-12-16 | — | — | WO | claimed |
| CN-110382582-A | Polyurethane foam and preparation method thereof | 科思创德国股份有限公司 | 2019-10-25 | — | — | CN | disclosed |
| US-20130140185-A1 | ELECTROLYTE AND PROCESS FOR THE DEPOSITION OF COPPER-TIN ALLOY LAYERS | UMICORE GALVANOTECHNIK GMBH (DE) | 2013-06-06 | — | — | US | disclosed |