SCHEMBL16290200

SCHEMBL16290200

CCCCC(N)OC(N)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.47
CA1 P00915 3/20 0.47
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 2/20 0.46
SLC1A3 P43003 1/20 0.46
DPP7 Q9UHL4 4/20 0.40
GRIK1 P39086 2/20 0.40
GRIK2 Q13002 2/20 0.40
SLC15A1 P46059 1/20 0.40
MAPK1 P28482 1/20 0.39
DPP8 Q6V1X1 3/20 0.37
DPP4 P27487 2/20 0.37
DPP9 Q86TI2 2/20 0.37
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
TP53 P04637 1/20 0.36
LAP3 P28838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27413544 0.92 GRIK1 (0.49) SLC1A2SLC1A1GRIK1GRIK2TP53
SCHEMBL27703023 0.86
SCHEMBL3079688 0.85 SLC1A2 (0.44) CA2CA1SLC1A2SLC1A1SLC1A3
SCHEMBL9282670 0.84 SLC1A2 (0.47) CA2CA1SLC1A2SLC1A1SLC1A3
SCHEMBL221495 0.83 SLC1A2 (0.46) CA2CA1SLC1A2SLC1A1SLC1A3
SCHEMBL15212136 0.81 CHRM2 (0.37) CA2CA1SLC1A2SLC1A1SLC1A3
SCHEMBL27922571 0.81 SLC1A2 (0.44) CA2CA1SLC1A2SLC1A1SLC1A3
SCHEMBL26666190 0.80 GSR (0.40) DPP7DPP8DPP4DPP9CHRM2
SCHEMBL27926569 0.80 LMNA (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL11598110 0.79 GRIK1 (0.46) CA1SLC1A2SLC1A1SLC1A3GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209448-A Cationic steroidal antimicrobial compounds and methods of making such compounds 布莱阿姆青年大学 2023-06-02 CN claimed
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-23 US disclosed
US-11891457-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 US disclosed
CN-116209669-A Cationic steroidal antimicrobial compounds with endogenous groups 布莱阿姆青年大学 2023-06-02 CN disclosed
CN-116209448-A Cationic steroidal antimicrobial compounds and methods of making such compounds 布莱阿姆青年大学 2023-06-02 CN disclosed
EP-2813512-B1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI PHARMACEUTICAL CO LTD (JP) 2021-03-31 EP disclosed
US-20210061860-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2021-03-04 US disclosed
US-20160311858-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-10-27 US disclosed
US-9409952-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-08-09 US disclosed
US-20150080549-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2015-03-19 US disclosed
EP-2813512-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD Chugai Seiyaku Kabushiki Kaisha (JP) 2014-12-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891457-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R CA2 2242/4885CA1 1024/4885SLC1A2 4271/4885
US-20210061860-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R CA2 2242/4885CA1 1024/4885SLC1A2 4271/4885
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R CA2 2242/4885CA1 1024/4885SLC1A2 4271/4885
US-20160311858-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R CA2 2242/4885CA1 1024/4885SLC1A2 4271/4885
US-20150080549-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R CA2 2242/4885CA1 1024/4885SLC1A2 4271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.