Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16290200 | 0.81 | CA2 (0.47) | CHRM2LMNACA1CA2SLC1A2 | |
| SCHEMBL27413544 | 0.78 | GRIK1 (0.49) | SLC1A2SLC1A1GRIK1GRIK2TP53 | |
| SCHEMBL27703023 | 0.77 | — | — | |
| SCHEMBL15212192 | 0.76 | CHRNB2 (0.37) | CHRM2LMNACHRM4CHRM5CHRM1 | |
| SCHEMBL15456105 | 0.73 | MMP1 (0.36) | CA1CA12CA9CA2SLC1A2 | |
| SCHEMBL28166380 | 0.73 | KDM5A (0.47) | CHRM2LMNACYP1A2CYP3A4HTR1A | |
| Carbamic Acid SCHEMBL28649191 | 0.72 | KDM5A (0.50) | CHRM2LMNACYP1A2CYP3A4HTR1A | |
| Acetone SCHEMBL27904025 | 0.72 | CA12 (0.54) | CHRM2LMNACYP1A2CYP3A4HTR1A | |
| SCHEMBL8399766 | 0.71 | FAAH (0.41) | CHRM2LMNACYP1A2CYP3A4HTR1A | |
| SCHEMBL9407962 | 0.71 | PLA2G1B (0.41) | CHRM2LMNACYP1A2CYP3A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184326-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2015-12-03 | — | — | WO | disclosed |
| WO-2015057847-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2015-04-23 | — | — | WO | disclosed |
| EP-2817345-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | Cerulean Pharma Inc. (US) | 2014-12-31 | — | — | EP | disclosed |
| US-20140037573-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC (US) | 2014-02-06 | — | — | US | disclosed |
| WO-2013126564-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2013-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140037573-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | SYNCRIP, EXOSC5, EXOSC9 | CHRM2 4830/4885LMNA 267/4885CYP1A2 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.