Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782968 | 0.80 | PGR (0.38) | CYP11B2CYP11B1 | |
| SCHEMBL16290492 | 0.80 | LAP3 (0.34) | LAP3KDM1ACYP11B2DRD2DRD3 | |
| SCHEMBL16307312 | 0.77 | CA1 (0.44) | CYP11B2CYP11B1DRD2DRD3 | |
| SCHEMBL16290364 | 0.77 | CA1 (0.44) | CYP11B2CYP11B1DRD2DRD3 | |
| SCHEMBL16307311 | 0.77 | CA1 (0.44) | CYP11B2CYP11B1DRD2DRD3 | |
| SCHEMBL16684186 | 0.76 | FFAR1 (0.30) | — | |
| SCHEMBL16290366 | 0.76 | FFAR1 (0.30) | — | |
| SCHEMBL16290334 | 0.74 | ACHE (0.31) | — | |
| SCHEMBL30015835 | 0.74 | IL1RN (0.32) | — | |
| SCHEMBL16290385 | 0.74 | HTR2A (0.34) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2865663-B1 | NOVEL INDANESULFAMIDE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2017-04-05 | — | — | EP | disclosed |
| EP-2865663-A1 | NOVEL INDANESULFAMIDE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2015-04-29 | — | — | EP | disclosed |
| US-9018260-B2 | Indanesulfamide derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20140371319-A1 | NOVEL INDANESULFAMlDE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371319-A1 | NOVEL INDANESULFAMlDE DERIVATIVES | SCN1A, SCN7A, SCN2A | LAP3 2798/4885KDM1A 847/4885CYP11B2 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.