Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL4622975 | 0.85 | PAOX (0.42) | TDP1TSHRPAOXANPEPALDH1A1 | |
| SCHEMBL162938 | 0.83 | TSHR (0.50) | TDP1TSHRPAOXANPEPALDH1A1 | |
| 1,3-Butanediol SCHEMBL162145 | 0.82 | ALDH1A1 (0.35) | TDP1TSHRPAOXANPEPALDH1A1 | |
| SCHEMBL11701066 | 0.81 | ANPEP (0.39) | TDP1TSHRPAOXANPEPALDH1A1 | |
| SCHEMBL1231151 | 0.81 | — | — | |
| L-Alaninol SCHEMBL11701058 | 0.81 | ANPEP (0.43) | TDP1TSHRPAOXANPEPALDH1A1 | |
| Propylene Glycol SCHEMBL8968542 | 0.80 | ALDH1A1 (0.59) | TDP1TSHRANPEPALDH1A1LMNA | |
| Diethanolamine SCHEMBL8017895 | 0.80 | TDP1 (0.59) | TDP1TSHRALDH1A1LMNACNR1 | |
| SCHEMBL23733297 | 0.79 | ANPEP (0.42) | TSHRPAOXANPEPALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL5436004 | 0.79 | ALDH1A1 (0.37) | TDP1TSHRPAOXANPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112888424-B | Film-forming cosmetic composition comprising polyurethane and crosslinked starch | 欧莱雅 | 2023-11-21 | — | — | CN | claimed |
| US-11779534-B2 | Film-forming cosmetic composition comprising polyurethane and cross-linked starch | L'OREAL (FR) | 2023-10-10 | — | — | US | claimed |
| CN-112888424-A | Film-forming cosmetic composition comprising polyurethane and cross-linked starch | 欧莱雅 | 2021-06-01 | — | — | CN | claimed |
| US-20210154128-A1 | FILM-FORMING COSMETIC COMPOSITION COMPRISING POLYURETHANE AND CROSS-LINKED STARCH | L'OREAL (FR) | 2021-05-27 | — | — | US | claimed |
| CN-101264048-B | Polyurethane dispersions for use in personal care products | BAYER MATERIALSCIENCE LLC | 2012-07-11 | — | — | CN | claimed |
| WO-2024133717-A1 | PROCESS FOR DYEING KERATIN HAIR FIBERS COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING A (POLY)CARBODIIMIDE COMPOUND, THE APPLICATION OF HEAT AND THE APPLICATION OF A COMPOSITION COMPRISING A (POLY)CARBODIIMIDE COMPOUND | L'OREAL (FR) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024133718-A1 | PROCESS FOR DYEING KERATIN HAIR FIBERS COMPRISING THE APPLICATION OF A COMPOSITION T COMPRISING AN AMINO ACID AND THE APPLICATION OF A (POLY)CARBODIIMIDE COMPOUND AND A COLOURING AGENT | L'OREAL (FR) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024133715-A1 | PROCESS FOR DYEING KERATIN HAIR FIBERS COMPRISING THE APPLICATION OF A TREATMENT WITH A REDUCING AGENT AND OF A COMPOSITION COMPRISING A (POLY)CARBODIIMIDE COMPOUND AND A COLOURING AGENT PROCESS FOR DYEING KERATIN HAIR FIBERS COMPRISING THE APPLICATION OF A TREATMENT WITH A REDUCING AGENT AND OF A COMPOSITION COMPRISING A (POLY)CARBODIIMIDE COMPOUND AND A COLOURING AGENT | L'OREAL (FR) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024133719-A1 | PROCESS FOR DYEING KERATIN HAIR FIBERS WHICH INVOLVES SPRAYING THE KERATIN HAIR FIBERS WITH A COMPOSITION COMPRISING A (POLY)CARBODIIMIDE COMPOUND AND A COLOURING AGENT USING AN AIRBRUSH | L'OREAL (FR) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024133693-A1 | PROCESS FOR DYEING KERATIN HAIR FIBERS COMPRISING THE APPLICATION OF A PARTICULAR COMPOSITION T AND THE APPLICATION OF A (POLY)CARBODIIMIDE COMPOUND AND A COLOURING AGENT | L'OREAL (FR) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024133697-A1 | PROCESS FOR DYEING KERATIN HAIR FIBERS COMPRISING THE APPLICATION OF A COLD PLASMA TREATMENT AND OF A COMPOSITION COMPRISING A (POLY)CARBODIIMIDE COMPOUND AND A COLOURING AGENT | L'OREAL (FR) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024133698-A1 | PROCESS FOR DYEING KERATIN HAIR FIBERS COMPRISING THE APPLICATION OF A (POLY)CARBODIIMIDE COMPOUND AND A COLOURING AGENT, THE APPLICATION OF STEAM AND SHAPING AT A PARTICULAR TEMPERATURE. | L'OREAL (FR) | 2024-06-27 | — | — | WO | disclosed |
| US-20070003866-A1 | Photosensitive composition, photosensitive planographic printing plate material, and image forming method of the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-01-04 | — | — | US | disclosed |
| US-7056644-B2 | Producing method of photosensitive planographic printing plate and printing plate produced thereby | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20050260524-A1 | Planographic printing plate material and preparing process of planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1586460-A1 | Planographic printing plate material and preparing process of planographic printing plate | Konica Minolta Medical & Graphic Inc. (JP) | 2005-10-19 | — | — | EP | disclosed |
| US-20050153237-A1 | Planographic printing plate material and preparing process of planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2005-07-14 | — | — | US | disclosed |
| EP-1553448-A2 | Planographic printing plate material and preparing process of planographic printing plate | Konica Minolta Medical & Graphic, Inc. (JP) | 2005-07-13 | — | — | EP | disclosed |
| US-20040219459-A1 | Producing method of photosensitive planographic printing plate and printing plate produced thereby | KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) | 2004-11-04 | — | — | US | disclosed |
| US-5102773-A | For production of printing plates | BASF AKTIENGESELLSCHAFT (DE) | 1992-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210154128-A1 | FILM-FORMING COSMETIC COMPOSITION COMPRISING POLYURETHANE AND CROSS-LINKED STARCH | CUTA, PUF60, PARG | TDP1 235/4885TSHR 4186/4885PAOX 744/4885 |
| US-11779534-B2 | Film-forming cosmetic composition comprising polyurethane and cross-linked starch | CUTA, PUF60, PARG | TDP1 235/4885TSHR 4186/4885PAOX 744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.