SCHEMBL1629134

SCHEMBL1629134

O=C(CI)NCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134099 0.78 ALDH1A1 (0.39)
SCHEMBL6980549 0.78
SCHEMBL6655925 0.78 ALDH1A1 (0.37)
SCHEMBL3954519 0.77
SCHEMBL15947374 0.77
SCHEMBL3305420 0.76 ALDH1A1 (0.41)
SCHEMBL7771371 0.75
SCHEMBL7771367 0.75
SCHEMBL8995940 0.73 ALDH1A1 (0.44)
SCHEMBL6980552 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2455102-B1 CANCER THERAPEUTIC AGENT COMPRISING ANTIBODY AGAINST CANCER-SPECIFIC MEMBRANE ANTIGEN ASAHI KASEI MEDICAL CO LTD (JP) 2017-03-15 EP disclosed
US-8637084-B2 Treatment method for epithelial cancerous organism ASAHI KASEI MEDICAL CO., LTD. (JP) 2014-01-28 US disclosed
EP-2455102-A1 CANCER THERAPEUTIC AGENT COMPRISING ANTIBODY AGAINST CANCER-SPECIFIC MEMBRANE ANTIGEN Asahi Kasei Kuraray Medical Co., Ltd. (JP) 2012-05-23 EP disclosed
US-20110091471-A1 TREATMENT METHOD FOR EPITHELIAL CANCEROUS ORGANISM ASAHI KASEI KURARAY MEDICAL CO., LTD. (JP) 2011-04-21 US disclosed
WO-2009031818-A2 BIOMARKER FOR PURIFICATION OR IDENTIFICATION OF MESENCHYMAL STEM CELLS AND METHODS OF PURIFICATION OF MESENCHYMAL STEM CELLS BY USING IT GENEXEL-SEIN. INC. (KR) 2009-03-12 WO disclosed
EP-0888779-B1 STERILE PROTECTIVE AGENT AND METHOD FOR STERILIZATION ASAHI MEDICAL CO (JP) 2003-07-02 EP disclosed
US-6572820-B2 Sterilization-protecting agent and sterilization method ASAHI MEDICAL CO., LTD. (JP) 2003-06-03 US disclosed
US-20020044884-A1 STERILIZATION- PROTECTING AGENT AND STERILIZATION METHOD ASAHI KASEI KURARAY MEDICAL CO., LTD. (JP) 2002-04-18 US disclosed
EP-1083226-A1 CELL SEPARATION DEVICE AND SEPARATION METHOD Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2001-03-14 EP disclosed
EP-0888779-A1 STERILE PROTECTIVE AGENT AND METHOD FOR STERILIZATION ASAHI MEDICAL CO., LTD. (JP) 1999-01-07 EP disclosed
EP-0621301-B1 ACYLAMIDOMETHYLATED POLYSULFONE AND PROCESS FOR PRODUCING THE SAME BIOMATERIAL RESEARCH INST CO L (JP) 1998-05-13 EP disclosed
EP-0390500-B1 Covalent attachment of macromolecules on substrate surfaces APPLIED IMMUNESCIENCES (US) 1996-06-05 EP disclosed
EP-0400920-B1 Solid phase multiple peptide synthesis APPLIED IMMUNESCIENCES (US) 1995-11-15 EP disclosed
US-5451438-A Molding material useful for absorption, separation and immobilization of bioactive materials BIOMATERIAL RESEARCH INSTITUTE CO., LTD. (JP) 1995-09-19 US disclosed
EP-0621301-A1 ACYLAMIDOMETHYLATED POLYSULFONE AND PROCESS FOR PRODUCING THE SAME BIOMATERIAL RESEARCH INSTITUTE CO., LTD. (JP) 1994-10-26 EP disclosed
US-5286789-A Clear polystyrene functionalized with linking groups APPLIED IMMUNE SCIENCES, INC. (US) 1994-02-15 US disclosed
EP-0400920-A1 Solid phase multiple peptide synthesis RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1990-12-05 EP disclosed
EP-0390500-A2 Covalent attachment of macromolecules on substrate surfaces APPLIED IMMUNESCIENCES, INC. (US) 1990-10-03 EP disclosed
US-4933410-A POLYSTYRENE DERIVATIZED UNDER FRIEDEL-CRAFTS CONDITIONS IN TETRAMETHYLENE SULFONE USING AN A-SUBSTITUTED-N-(Y-METHYL)ACETAMIDE APPLIED IMMUNESCIENCES, INC. (US) 1990-06-12 US disclosed