Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143585 | 0.85 | SMN1; SMN2 (0.48) | ALDH1A1PPIDPOLBRXFP1L3MBTL1 | |
| SCHEMBL10503169 | 0.82 | KIF11 (0.42) | — | |
| SCHEMBL16291478 | 0.82 | KIF11 (0.42) | ALDH1A1 | |
| SCHEMBL9373019 | 0.80 | ALDH1A1 (0.61) | ALDH1A1PPIDPOLBRXFP1GAA | |
| SCHEMBL13177607 | 0.80 | KIF11 (0.44) | — | |
| SCHEMBL14401044 | 0.78 | MEN1 (0.37) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL23956928 | 0.77 | KIF11 (0.58) | ALDH1A1GAAHPGDMEN1KMT2A | |
| SCHEMBL17245967 | 0.76 | KIF11 (0.43) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6574289 | 0.76 | KIF11 (0.43) | POLBRXFP1 | |
| SCHEMBL1364085 | 0.76 | KIF11 (0.49) | ALDH1A1POLBRXFP1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9044519-B2 | Radiotracer precursor for imaging of hypoxic tissue, radiotracer, and method for preparing the same | Atomic Energy Council—Institute of Nuclear Energy Research (TW) | 2015-06-02 | — | — | US | claimed |
| US-20140371434-A1 | RADIOTRACER PRECURSOR FOR IMAGING OF HYPOXIC TISSUE, RADIOTRACER, AND METHOD FOR PREPARING THE SAME | ATOMIC ENERGY COUNCIL-INSTTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2014-12-18 | — | — | US | claimed |
| US-9044519-B2 | Radiotracer precursor for imaging of hypoxic tissue, radiotracer, and method for preparing the same | Atomic Energy Council—Institute of Nuclear Energy Research (TW) | 2015-06-02 | — | — | US | disclosed |
| US-9044519-B2 | Radiotracer precursor for imaging of hypoxic tissue, radiotracer, and method for preparing the same | Atomic Energy Council—Institute of Nuclear Energy Research (TW) | 2015-06-02 | — | — | US | disclosed |
| US-20140371434-A1 | RADIOTRACER PRECURSOR FOR IMAGING OF HYPOXIC TISSUE, RADIOTRACER, AND METHOD FOR PREPARING THE SAME | ATOMIC ENERGY COUNCIL-INSTTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2014-12-18 | — | — | US | disclosed |
| US-20140371434-A1 | RADIOTRACER PRECURSOR FOR IMAGING OF HYPOXIC TISSUE, RADIOTRACER, AND METHOD FOR PREPARING THE SAME | ATOMIC ENERGY COUNCIL-INSTTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371434-A1 | RADIOTRACER PRECURSOR FOR IMAGING OF HYPOXIC TISSUE, RADIOTRACER, AND METHOD FOR PREPARING THE SAME | HIF1A, HIF1AN, HYOU1 | ALDH1A1 528/4885PPID 2119/4885POLB 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.