Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | FPR3 | P25089 | 1/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15995479 | 0.93 | ALDH1A1 (0.64) | CHRM2ALDH1A1ALOX15TSHRL3MBTL1 | |
| SCHEMBL5024894 | 0.87 | ALDH1A1 (0.76) | CHRM2ALDH1A1ALOX15TSHRL3MBTL1 | |
| SCHEMBL5028870 | 0.85 | ALDH1A1 (0.74) | CHRM2ALDH1A1ALOX15TSHRL3MBTL1 | |
| SCHEMBL16741961 | 0.83 | CHRM2 (0.92) | CHRM2ALDH1A1ALOX15TSHRL3MBTL1 | |
| SCHEMBL9777421 | 0.80 | CHRM2 (0.93) | CHRM2ALDH1A1ALOX15TSHRL3MBTL1 | |
| SCHEMBL6231722 | 0.79 | CHRM2 (0.85) | CHRM2ALDH1A1ALOX15TSHRL3MBTL1 | |
| SCHEMBL16006928 | 0.79 | CYP3A4 (0.43) | CHRM2ALDH1A1ALOX15TSHRL3MBTL1 | |
| SCHEMBL9184672 | 0.78 | CHRM2 (0.89) | CHRM2ALDH1A1ALOX15TSHRL3MBTL1 | |
| SCHEMBL19937803 | 0.77 | SCN8A (0.53) | CHRM2ALDH1A1ALOX15TSHRL3MBTL1 | |
| SCHEMBL5024742 | 0.77 | L3MBTL1 (1.00) | CHRM2ALDH1A1ALOX15TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221801-B2 | Inhibitors of histone demethylases | EPITHERAPEUTICS APS (DK) | 2015-12-29 | — | — | US | disclosed |
| US-20140371214-A1 | INHIBITORS OF HISTONE DEMETHYLASES | GILEAD SCIENCES, INC. | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371214-A1 | INHIBITORS OF HISTONE DEMETHYLASES | KDM1B, KDM1A, KDM3A | CHRM2 3004/4885ALDH1A1 1536/4885ALOX15 1831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.