Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.85 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.64 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184672 | 0.98 | CHRM2 (0.89) | CHRM2SCN8ASIRT2ALOX15KDM4E | |
| SCHEMBL9777421 | 0.96 | CHRM2 (0.93) | CHRM2SCN8ASIRT2ALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL10698987 | 0.96 | CHRM2 (0.86) | CHRM2SCN8ASIRT2ALOX15KDM4E | |
| SCHEMBL9188072 | 0.96 | CHRM2 (0.86) | CHRM2SCN8ASIRT2ALOX15KDM4E | |
| SCHEMBL9777408 | 0.96 | CHRM2 (0.86) | CHRM2SCN8ASIRT2ALOX15KDM4E | |
| SCHEMBL16741961 | 0.96 | CHRM2 (0.92) | CHRM2SCN8ASIRT2ALOX15KDM4E | |
| SCHEMBL9777405 | 0.94 | CHRM2 (0.83) | CHRM2SCN8ASIRT2ALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL10617762 | 0.94 | CHRM2 (0.83) | CHRM2SCN8ASIRT2ALOX15KDM4E | |
| SCHEMBL348655 | 0.91 | CHRM2 (0.78) | CHRM2SCN8ASIRT2ALOX15KDM4E | |
| SCHEMBL6205124 | 0.91 | CHRM2 (0.72) | CHRM2SCN8ASIRT2ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050085555-A1 | Composition, synthesis and therapeutic applications of polyamines | MURPHY, MICHAEL A. | 2005-04-21 | — | — | US | claimed |
| WO-2023183559-A1 | ENGINEERED IONOPHORES FOR TRANSPORT OF METAL IONS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| US-20160225472-A1 | POLYMERIC CHELATORS FOR METAL ION EXTRACTION AND SEPARATION | UNIV TEXAS (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160225471-A1 | FUNCTIONAL CONDUCTING POLYMERS FOR REDOX MEDIATED SEPARATIONS OF F-ELEMENTS | UNIV TEXAS (US) | 2016-08-04 | — | — | US | disclosed |
| WO-2015076911-A2 | FUNCTIONAL CONDUCTING POLYMERS FOR REDOX MEDIATED SEPARATIONS OF F-ELEMENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-05-28 | — | — | WO | disclosed |
| US-20140057877-A1 | Therapeutic polyamine compositions and their synthesis | MURPHY MICHAEL A (US) | 2014-02-27 | — | — | US | disclosed |
| EP-1165738-B1 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2005-07-27 | — | — | EP | disclosed |
| US-20050085555-A1 | Composition, synthesis and therapeutic applications of polyamines | MURPHY, MICHAEL A. | 2005-04-21 | — | — | US | disclosed |
| EP-1465611-A2 | COMPOSITION, SYNTHESIS AND THERAPEUTIC APPLICATIONS OF POLYAMINES | Murphy, Michael A. (US) | 2004-10-13 | — | — | EP | disclosed |
| US-6617299-B1 | Contacting the textile with a ligand which forms a complex with a transition metal, whereby the complex catalyses bleaching of the textile by atmospheric oxygen without use of aldehydes, wherein at | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-09-09 | — | — | US | disclosed |
| WO-2003051348-A2 | COMPOSITION, SYNTHESIS AND THERAPEUTIC APPLICATIONS OF POLYAMINES | MURPHY MICHAEL A (US) | 2003-06-26 | — | — | WO | disclosed |
| US-20030013772-A1 | Composition, synthesis and therapeutic applications of polyamines | MURPHY, MICHAEL A. | 2003-01-16 | — | — | US | disclosed |
| EP-1165738-A1 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000060044-A1 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2000-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013772-A1 | Composition, synthesis and therapeutic applications of polyamines | TXN2, PYCR1, SQOR | CHRM2 195/4885SCN8A 3640/4885SIRT2 1143/4885 |
| US-20050085555-A1 | Composition, synthesis and therapeutic applications of polyamines | PRDX5, PINK1, ARG2 | CHRM2 549/4885SCN8A 4788/4885SIRT2 1818/4885 |
| US-20140057877-A1 | Therapeutic polyamine compositions and their synthesis | MCU, PC, PINK1 | CHRM2 705/4885SCN8A 4794/4885SIRT2 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.