Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL3051584 | 0.96 | ALDH1A1 (0.45) | LMNATP53GMNNALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL1627398 | 0.96 | ALDH1A1 (0.45) | LMNATP53GMNNALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL7530825 | 0.92 | LMNA (0.43) | LMNATP53GMNNALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL15710440 | 0.92 | LMNA (0.43) | LMNATP53GMNNALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL1436085 | 0.88 | ALDH1A1 (0.45) | LMNATP53GMNNALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL11238338 | 0.88 | ALDH1A1 (0.45) | LMNATP53GMNNALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL3145097 | 0.88 | ALDH1A1 (0.45) | LMNATP53GMNNALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL9745986 | 0.88 | ALDH1A1 (0.45) | LMNATP53GMNNALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL1889469 | 0.88 | ALDH1A1 (0.45) | LMNATP53GMNNALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL11549839 | 0.88 | ALDH1A1 (0.45) | LMNATP53GMNNALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886979-B1 | Coordinated Metal Compounds for reducing chromium | GRACE W R & CO (US) | 2012-09-26 | — | — | EP | disclosed |
| US-7927418-B2 | Coordinated metal compounds for reducing chromium | W. R. GRACE & CO.-CONN. (US) | 2011-04-19 | — | — | US | disclosed |
| US-20100162925-A1 | Coordinated Metal Compounds for Reducing Chromium | VERIFI LLC | 2010-07-01 | — | — | US | disclosed |
| WO-2008021966-A2 | COORDINATED METAL COMPOUNDS FOR REDUCING CHROMIUM | W.R. GRACE & CO.-CONN. (US) | 2008-02-21 | — | — | WO | disclosed |
| EP-1886979-A2 | Coordinated Metal Compounds for reducing chromium | W.R. Grace & Co.-Conn. (US) | 2008-02-13 | — | — | EP | disclosed |