Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 13/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.56 |
| ▸ | BLM | P54132 | 5/20 | 0.56 |
| ▸ | GLA | P06280 | 5/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 12/20 | 0.54 |
| ▸ | GAA | P10253 | 9/20 | 0.54 |
| ▸ | POLB | P06746 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295296 | 0.85 | KDM4E (0.60) | CUL4AMEN1KMT2AKDM4EBLM | |
| SCHEMBL3590531 | 0.85 | ADORA2A (0.57) | CUL4AMEN1KMT2AKDM4EBLM | |
| SCHEMBL6445065 | 0.84 | CUL4A (0.64) | CUL4AMEN1KMT2AKDM4EBLM | |
| SCHEMBL16295718 | 0.83 | MAPT (0.76) | CUL4AMEN1KMT2AKDM4EBLM | |
| SCHEMBL14584409 | 0.83 | MAPT (0.69) | CUL4AMEN1KMT2AKDM4EBLM | |
| SCHEMBL3032558 | 0.82 | KDM4E (0.80) | CUL4AMEN1KMT2AKDM4EBLM | |
| SCHEMBL15571075 | 0.80 | CUL4A (1.00) | CUL4AMEN1KMT2AKDM4EBLM | |
| SCHEMBL12822457 | 0.77 | CUL4A (0.56) | CUL4AMEN1KMT2AKDM4EBLM | |
| SCHEMBL6441223 | 0.75 | ALDH1A1 (0.61) | CUL4AMEN1KMT2AKDM4EBLM | |
| SCHEMBL14955233 | 0.73 | ALDH1A1 (0.59) | CUL4AMEN1KMT2AKDM4EBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2022-07-05 | — | — | US | disclosed |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2020-07-09 | — | — | US | disclosed |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| WO-2014201326-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2014-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | CUL4A 857/4885MEN1 4484/4885KMT2A 1738/4885 |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | CUL4A 857/4885MEN1 4484/4885KMT2A 1738/4885 |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | CUL4A 857/4885MEN1 4484/4885KMT2A 1738/4885 |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | CUL4A 857/4885MEN1 4484/4885KMT2A 1738/4885 |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | CUL4A 857/4885MEN1 4484/4885KMT2A 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.