Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.46 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16294552 | 0.85 | ADORA2A (0.57) | ADORA2AADORA1ADORA2BKMT2AALDH1A1 | |
| SCHEMBL16295312 | 0.81 | KMT2A (0.55) | ADORA2AADORA1KMT2AALDH1A1HPGD | |
| SCHEMBL16294986 | 0.78 | ADORA2A (0.57) | ADORA2AADORA1ADORA2BKMT2AALDH1A1 | |
| SCHEMBL5320925 | 0.76 | ADORA2A (0.74) | ADORA2AADORA1ADORA2BKMT2AALDH1A1 | |
| SCHEMBL16295045 | 0.76 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BKMT2AALDH1A1 | |
| SCHEMBL16295093 | 0.75 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BKMT2AALDH1A1 | |
| SCHEMBL5325584 | 0.74 | ADORA2A (0.57) | ADORA2AADORA1ADORA2BKMT2AALDH1A1 | |
| SCHEMBL3581858 | 0.74 | ADORA2A (0.74) | ADORA2AADORA1ADORA2BKMT2AALDH1A1 | |
| SCHEMBL14596750 | 0.73 | KMT2A (0.67) | ADORA2AADORA1KMT2AALDH1A1HPGD | |
| SCHEMBL29682369 | 0.73 | KMT2A (0.58) | ADORA2AADORA1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2020-02-04 | — | — | US | claimed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | claimed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | claimed |
| WO-2014201326-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2014-12-18 | — | — | WO | claimed |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2022-07-05 | — | — | US | disclosed |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2022-07-05 | — | — | US | disclosed |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2020-07-09 | — | — | US | disclosed |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2020-07-09 | — | — | US | disclosed |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2020-02-04 | — | — | US | disclosed |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| WO-2014201326-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2014-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | ADORA2A 3836/4885ADORA1 3901/4885ADORA2B 4338/4885 |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | ADORA2A 3836/4885ADORA1 3901/4885ADORA2B 4338/4885 |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | ADORA2A 3836/4885ADORA1 3901/4885ADORA2B 4338/4885 |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | ADORA2A 3836/4885ADORA1 3901/4885ADORA2B 4338/4885 |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | ADORA2A 3836/4885ADORA1 3901/4885ADORA2B 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.