SCHEMBL16295170

SCHEMBL16295170

C[Si](C)(C)OCCCCCCCCCCCC(=O)O[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.39
ALDH1A1 P00352 3/20 0.36
LMNA P02545 4/20 0.33
TSHR P16473 2/20 0.33
DNM1 Q05193 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
PAM P19021 2/20 0.32
MAPT P10636 2/20 0.32
MAPK1 P28482 1/20 0.32
NAAA Q02083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8463255 0.87 DGKA (0.43) DGKAALDH1A1LMNATSHRDNM1
SCHEMBL16295140 0.87 DGKA (0.43) DGKAALDH1A1LMNATSHRDNM1
SCHEMBL8465959 0.87 DGKA (0.43) DGKAALDH1A1LMNATSHRDNM1
SCHEMBL8463526 0.87 DGKA (0.43) DGKAALDH1A1LMNATSHRDNM1
SCHEMBL134075 0.85 TSHR (0.43) DGKAALDH1A1LMNATSHRDNM1
SCHEMBL16294270 0.84 TSHR (0.54) DGKAALDH1A1LMNATSHR
SCHEMBL16294179 0.84 TSHR (0.54) DGKAALDH1A1LMNATSHR
SCHEMBL18038087 0.84 TSHR (0.54) DGKAALDH1A1LMNATSHR
SCHEMBL7759649 0.82 DGKA (0.38) DGKAALDH1A1LMNATSHRDNM1
SCHEMBL13044430 0.81 DGKA (0.50) DGKAALDH1A1TSHRDNM1PAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595495-B2 Methods of producing omega-hydroxylated fatty acid derivatives GENOMATICA, INC. (US) 2026-04-07 US disclosed
US-20250019731-A1 Methods Of Producing Omega-Hydroxylated Fatty Acid Derivatives AGAIN BIO APS (DK) 2025-01-16 US disclosed
CN-105378486-B Process for producing OMEGA-hydroxylated fatty acid derivatives 基因组股份公司 2024-05-14 CN disclosed
US-11981952-B2 Methods of producing omega-hydroxylated fatty acid derivatives GENOMATICA, INC. (US) 2024-05-14 US disclosed
US-20210189439-A1 Multifunctional Fatty Acid Derivatives And Biosynthesis Thereof GENOMATICA, INC. (US) 2021-06-24 US disclosed
EP-3810778-A1 MULTIFUNCTIONAL FATTY ACID DERIVATIVES AND BIOSYNTHESIS THEREOF Genomatica, Inc. (US) 2021-04-28 EP disclosed
US-20210071212-A1 METHODS OF PRODUCING OMEGA-HYDROXYLATED FATTY ACID DERIVATIVES GENOMATICA, INC. (US) 2021-03-11 US disclosed
EP-3745133-A1 METHODS OF PRODUCING OMEGA-HYDROXYLATED FATTY ACID DERIVATIVES Genomatica, Inc. (US) 2020-12-02 EP disclosed
US-10711288-B2 Methods of producing omega-hydroxylated fatty acid derivatives GENOMATICA, INC. (US) 2020-07-14 US disclosed
EP-2984490-B1 METHODS OF PRODUCING OMEGA-HYDROXYLATED FATTY ACID DERIVATIVES GENOMATICA INC (US) 2020-05-20 EP disclosed
WO-2019217226-A1 MULTIFUNCTIONAL FATTY ACID DERIVATIVES AND BIOSYNTHESIS THEREOF REG Life Sciences, LLC (US) 2019-11-14 WO disclosed
US-20160130616-A1 METHODS OF PRODUCING OMEGA-HYDROXYLATED FATTY ACID DERIVATIVES AGAIN BIO APS (DK) 2016-05-12 US disclosed
EP-2984490-A1 METHODS OF PRODUCING OMEGA-HYDROXYLATED FATTY ACID DERIVATIVES REG Life Sciences, LLC (US) 2016-02-17 EP disclosed
WO-2014201474-A1 METHODS OF PRODUCING OMEGA-HYDROXYLATED FATTY ACID DERIVATIVES LS9, INC. (US) 2014-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595495-B2 Methods of producing omega-hydroxylated fatty acid derivatives CYP4F11, CYP2F1, CYP4Z1 DGKA 982/4885ALDH1A1 327/4885LMNA 3439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.