SCHEMBL162990

SCHEMBL162990

COc1c(C)c(Br)c(Br)c(Br)c1-c1c(O)ccc(C)c1C

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
MAOA P21397 1/20 0.31
SCN5A Q14524 1/20 0.30
NCEH1 Q6PIU2 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10785882 0.74 MGAM (0.34) ESR1ESR2MGAMGAASI
SCHEMBL6227967 0.74 TRPA1 (0.48) ESR1ESR2GAAMAOAPTGS1
SCHEMBL158804 0.72 MGAM (0.35) ESR1ESR2MGAMGAASI
SCHEMBL10460608 0.70 MAOA (0.43) ESR1ESR2MAOASCN5A
SCHEMBL768018 0.67 SCN5A (0.52) ESR1ESR2MAOASCN5A
SCHEMBL11750586 0.67 MAOA (0.43) ESR1ESR2MGAMGAASI
SCHEMBL11344934 0.66 TDP1 (0.41) ESR1ESR2MGAMGAASI
SCHEMBL30972746 0.66 TRPA1 (0.44) ESR1ESR2GAASCN5ANCEH1
SCHEMBL2168487 0.66 TRPA1 (0.44) ESR1ESR2GAASCN5ANCEH1
SCHEMBL29421886 0.64 MAOA (0.44) ESR1ESR2MAOASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2794713-B1 TOUGHENING AGENT FOR EPOXY THERMOSET DOW GLOBAL TECHNOLOGIES LLC (US) 2017-09-06 EP claimed
US-9657118-B2 Toughening agent for epoxy thermoset DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-23 US claimed
WO-2017030754-A1 EPOXY MATERIALS WITH IMPROVED PROCESSABILITY AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-23 WO claimed
WO-2017027201-A1 EPOXY MATERIALS WITH IMPROVED PROCESSABILITY AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-16 WO claimed
WO-2017027199-A1 EPOXY MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-16 WO claimed
WO-2017027200-A1 EPOXY THERMOSET MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-16 WO claimed
WO-2017019679-A1 EPOXY MATERIALS AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-02 WO claimed
WO-2017019677-A1 EPOXY THERMOSET MATERIALS AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-02 WO claimed
US-9006385-B2 Elastomeric epoxy materials and the use thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2015-04-14 US claimed
EP-2611849-B1 ELASTOMERIC INSULATION MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-03-18 EP claimed
WO-2012030339-A1 ELASTOMERIC INSULATION MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-08 WO claimed
WO-2012030338-A1 ELASTOMERIC EPOXY MATERIALS AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-08 WO claimed
US-7592067-B2 Epoxy resin compositions, processes utilizing same and articles made therefrom HEXION SPECIALTY CHEMICALS, INC. (US) 2009-09-22 US claimed
US-20060217516-A1 Tertiary amine modified polyurethane products made therefrom CASATI FRANCOIS M 2006-09-28 US claimed
US-20060052570-A1 Amine-epoxy autocatalytic polymers and polyurethane products made therefrom GAN JOSEPH 2006-03-09 US claimed
EP-1470174-A1 TERTIARY AMINE MODIFIED POLYOLS AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-10-27 EP claimed
WO-2003055930-A1 TERTIARY AMINE MODIFIED POLYOLS AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2003-07-10 WO claimed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US claimed
US-4725652-A TETRASUBSTITUTED ONIUM COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1988-02-16 US claimed
US-4665149-A Triazine containing epoxy resins having improved thermal stability THE DOW CHEMICAL COMPANY (US) 1987-05-12 US claimed