SCHEMBL158804

SCHEMBL158804

COc1c(Br)c(Br)c(Br)c(Br)c1-c1c(O)cc(C)c(C)c1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
PIM1 P11309 1/20 0.34
CYP3A4 P08684 1/20 0.33
IMPDH2 P12268 1/20 0.33
TPMT P51580 1/20 0.33
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
PTPN1 P18031 2/20 0.32
PDE4B Q07343 2/20 0.31
DRD2 P14416 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1245515 0.79 TDP1 (0.39) TDP1PIM1CYP3A4IMPDH2PDE4B
SCHEMBL162989 0.77 KDM4E (0.37) TDP1CYP3A4KDM4EMEN1USP2
SCHEMBL994122 0.75 MAPT (0.46) GAATDP1PIM1CYP3A4CA2
SCHEMBL10787473 0.73 GAA (0.36) MGAMGAASIMGAM2TDP1
SCHEMBL162990 0.72 ESR1 (0.37) MGAMGAASIMGAM2PTGS1
SCHEMBL4622981 0.72 TDP1 (0.52) TDP1CYP3A4IMPDH2TPMTPTPN1
SCHEMBL11344934 0.71 TDP1 (0.41) MGAMGAASIMGAM2TDP1
SCHEMBL18838160 0.69 HSD17B10 (0.39) TDP1PIM1CYP3A4TPMTCA2
SCHEMBL8249793 0.68 TDP1 (0.52) TDP1CYP3A4IMPDH2TPMTPTPN1
SCHEMBL7173958 0.67 ALDH1A1 (0.40) GAATDP1CYP3A4CA2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2794713-B1 TOUGHENING AGENT FOR EPOXY THERMOSET DOW GLOBAL TECHNOLOGIES LLC (US) 2017-09-06 EP claimed
US-9657118-B2 Toughening agent for epoxy thermoset DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-23 US claimed
WO-2017030754-A1 EPOXY MATERIALS WITH IMPROVED PROCESSABILITY AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-23 WO claimed
WO-2017027201-A1 EPOXY MATERIALS WITH IMPROVED PROCESSABILITY AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-16 WO claimed
WO-2017027199-A1 EPOXY MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-16 WO claimed
WO-2017027200-A1 EPOXY THERMOSET MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-16 WO claimed
WO-2017019677-A1 EPOXY THERMOSET MATERIALS AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-02 WO claimed
WO-2017019679-A1 EPOXY MATERIALS AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-02 WO claimed
US-9006385-B2 Elastomeric epoxy materials and the use thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2015-04-14 US claimed
EP-2611849-B1 ELASTOMERIC INSULATION MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-03-18 EP claimed
WO-2004060956-A1 AMINE-EPOXY AUTOCATALYTIC POLYMERS AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-07-22 WO claimed
WO-2003055930-A1 TERTIARY AMINE MODIFIED POLYOLS AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2003-07-10 WO claimed
US-6168898-B1 A POSITIVE ACTING, PHOTOIMAGEABLE COMPOSITION HAVING, A PHOTOACID GENERATOR CAPABLE OF GENERATING AN ACID UPON EXPOSURE TO ACTINIC RADIATION, A STYRENE-MALEIC ANHYDRIDE COPOLYMER, AN EPXOY, AND A CURING CATALYST ISOLA LAMINATE SYSTEMS CORP. 2001-01-02 US claimed
EP-1062545-A1 POSITIVE ACTING PHOTODIELECTRIC COMPOSITION Isola Laminate Systems Corporation (US) 2000-12-27 EP claimed
EP-0976307-A1 POSITIVE WORKING PHOTODEFINABLE RESIN COATED METAL FOR MASS PRODUCTION OF MICROVIAS IN MULTILAYER PRINTED WIRING BOARDS AlliedSignal Inc. (US) 2000-02-02 EP claimed
WO-1999041642-A1 POSITIVE ACTING PHOTODIELECTRIC COMPOSITION ISOLA LAMINATE SYSTEMS CORPORATION (US) 1999-08-19 WO claimed
WO-1998047332-A1 POSITIVE WORKING PHOTODEFINABLE RESIN COATED METAL FOR MASS PRODUCTION OF MICROVIAS IN MULTILAYER PRINTED WIRING BOARDS ALLIEDSIGNAL INC. (US) 1998-10-22 WO claimed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US claimed
US-4725652-A TETRASUBSTITUTED ONIUM COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1988-02-16 US claimed
US-4665149-A Triazine containing epoxy resins having improved thermal stability THE DOW CHEMICAL COMPANY (US) 1987-05-12 US claimed