SCHEMBL1629915

SCHEMBL1629915

[C-]#[N+]c1cccc(C=Cc2cccc(C#N)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 3/20 0.50
P4HB P07237 11/20 0.44
GRIN2D O15399 2/20 0.42
GRIN3B O60391 2/20 0.42
GRIN1 Q05586 2/20 0.42
GRIN2A Q12879 2/20 0.42
GRIN2B Q13224 2/20 0.42
GRIN2C Q14957 2/20 0.42
GRIN3A Q8TCU5 2/20 0.42
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
HRH4 Q9H3N8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12230306 0.97 FBP1 (0.48) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL1629913 0.90 FBP1 (0.50) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL1629990 0.90 FBP1 (0.50) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL12230308 0.89 FBP1 (0.39) FBP1P4HBMAOAMAOB
SCHEMBL3594003 0.84 ENPP2 (0.44) MAOB
SCHEMBL29953534 0.84 ENPP2 (0.44) MAOB
SCHEMBL2774364 0.84 FBP1 (0.65) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL1687910 0.84 FBP1 (0.65) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL1629352 0.81 FBP1 (0.43) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL9186668 0.80 FBP1 (0.61) FBP1P4HBGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8835084-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2014-09-16 US disclosed
US-20120087695-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-04-12 US disclosed