Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3594003 | 1.00 | ENPP2 (0.44) | ENPP2TSHRCLK4GSK3BDRD2 | |
| SCHEMBL1629915 | 0.84 | FBP1 (0.50) | MAOB | |
| SCHEMBL12230306 | 0.81 | FBP1 (0.48) | MAOB | |
| SCHEMBL11930766 | 0.81 | CLK4 (0.54) | TSHRCLK4ALDH1A1MAPTIDO1 | |
| SCHEMBL12271100 | 0.81 | ENPP2 (0.57) | ENPP2TSHRCLK4GSK3BDRD2 | |
| SCHEMBL12417362 | 0.81 | CLK4 (0.36) | ENPP2TSHRCLK4GSK3BDRD2 | |
| SCHEMBL28592899 | 0.80 | ENPP2 (0.45) | ENPP2TSHRCLK4GSK3BDRD2 | |
| SCHEMBL11930765 | 0.80 | CLK4 (0.53) | TSHRCLK4ALDH1A1MAPTIDO1 | |
| SCHEMBL13170987 | 0.78 | PGR (0.47) | CLK4ALDH1A1 | |
| SCHEMBL12408530 | 0.78 | TBXAS1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |