Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 4/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179242 | 0.90 | CA1 (0.45) | CA1CA2LPLLIPGTRPV1 | |
| SCHEMBL28411255 | 0.83 | IGF1R (0.46) | CA1CA2LPLLIPGTRPV1 | |
| SCHEMBL16299510 | 0.83 | SPHK2 (0.47) | SIGMAR1SPHK2SPHK1TRPV1 | |
| SCHEMBL3653415 | 0.83 | ESR1 (0.55) | SIGMAR1CA2TRPV1MGLL | |
| SCHEMBL14116837 | 0.81 | TAAR1 (0.41) | SIGMAR1CA1CA2LPLLIPG | |
| SCHEMBL16299512 | 0.81 | SPHK2 (0.42) | SIGMAR1SPHK2SPHK1 | |
| SCHEMBL2820906 | 0.81 | TRPA1 (0.50) | SIGMAR1TRPV1 | |
| SCHEMBL11440803 | 0.79 | MMP12 (0.53) | — | |
| SCHEMBL5950465 | 0.78 | MMP12 (0.44) | CA1CA2LPLLIPGTRPV1 | |
| SCHEMBL28187174 | 0.76 | TRPA1 (0.46) | SIGMAR1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871375-B1 | CARBOLINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | PTC THERAPEUTICS INC (US) | 2012-02-29 | — | — | EP | disclosed |