Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRPR | P30550 | 14/20 | 0.72 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.60 |
| ▸ | ITGAV | P06756 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14864723 | 0.94 | GRPR (0.72) | GRPRITGB3ITGAV | |
| SCHEMBL4344249 | 0.92 | GRPR (0.69) | GRPR | |
| SCHEMBL14412222 | 0.92 | GRPR (0.85) | GRPR | |
| SCHEMBL13906646 | 0.92 | GRPR (0.85) | GRPR | |
| SCHEMBL5350846 | 0.91 | GRPR (0.66) | GRPR | |
| SCHEMBL1413932 | 0.91 | GRPR (0.68) | GRPR | |
| SCHEMBL1413933 | 0.91 | GRPR (0.68) | GRPR | |
| SCHEMBL4352525 | 0.91 | GRPR (0.67) | GRPR | |
| SCHEMBL4352522 | 0.91 | GRPR (0.67) | GRPR | |
| SCHEMBL28758393 | 0.89 | GRPR (0.67) | GRPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178906-A1 | CHELATION OF METALS TO THIOL GROUPS USING IN SITU REDUCTION OF DISULFIDE-CONTAINING COMPOUNDS BY PHOSPHINES | BRACCO IMAGING S.P.A. (IT) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178906-A1 | CHELATION OF METALS TO THIOL GROUPS USING IN SITU REDUCTION OF DISULFIDE-CONTAINING COMPOUNDS BY PHOSPHINES | TST, PTMS, MPST | GRPR 577/4885ITGB3 3078/4885ITGAV 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.