Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15541381 | 0.82 | HRH3 (0.46) | LTA4HHRH3ADRB2CYSLTR1MEN1 | |
| SCHEMBL15417787 | 0.81 | SMN1; SMN2 (0.41) | HRH3ADRB2KMT2ANPC1RAB9A | |
| SCHEMBL17826373 | 0.80 | HRH3 (0.41) | LTA4HHRH3ADRB2 | |
| SCHEMBL14922940 | 0.79 | DRD2 (0.41) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL23783484 | 0.78 | ABCG2 (0.46) | HRH3ADRB2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16301018 | 0.77 | ADRB2 (0.33) | ADRB2CA12CA1CA2CA4 | |
| SCHEMBL26079051 | 0.77 | TDP1 (0.47) | TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24438026 | 0.77 | APP (0.45) | — | |
| SCHEMBL15385189 | 0.77 | ADRB2 (0.31) | ADRB2 | |
| SCHEMBL13866492 | 0.76 | KCNA3 (0.44) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479171-A1 | CHROMENE COMPOUND | Tokuyama Corporation (JP) | 2012-07-25 | — | — | EP | disclosed |