Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15417787 | 0.82 | SMN1; SMN2 (0.41) | L3MBTL1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL15385189 | 0.82 | ADRB2 (0.31) | — | |
| SCHEMBL13820168 | 0.82 | DRD2 (0.48) | DRD2DRD4DRD3WDR5L3MBTL1 | |
| SCHEMBL24438026 | 0.82 | APP (0.45) | KCNH2 | |
| SCHEMBL26079051 | 0.82 | TDP1 (0.47) | L3MBTL1NPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL26193250 | 0.81 | KMT2A (0.41) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13866492 | 0.81 | KCNA3 (0.44) | DRD2DRD4DRD3KCNH2 | |
| SCHEMBL22764589 | 0.80 | DRD2 (0.52) | DRD2DRD4DRD3L3MBTL1KCNH2 | |
| SCHEMBL16301061 | 0.79 | LTA4H (0.41) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL15923042 | 0.77 | DRD2 (0.49) | DRD2DRD4DRD3L3MBTL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167887-A1 | ARYL AMINE SUBSTITUTED QUINOXALINE USED AS ANTICANCER DRUGS | Chen, Kuenfeng (TW) | 2017-05-17 | — | — | EP | disclosed |
| WO-2015189331-A1 | USE AS RODENTICIDES OF COMPOUNDS THAT INHIBIT BLOOD COAGULATION | GULBA DIETRICH (DE) | 2015-12-17 | — | — | WO | disclosed |
| EP-2918590-A1 | COMPOSITION FOR CHARGE-TRANSPORT FILM AND IONIC COMPOUND, CHARGE-TRANSPORT FILM AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME, AND PRODUCTION METHOD OF THE ORGANIC ELECTROLUMINESCENCE DEVICE AND PRODUCTION METHOD OF THE CHARGE-TRANSPORT FILM | Mitsubishi Chemical Corporation (JP) | 2015-09-16 | — | — | EP | disclosed |
| EP-2842956-A1 | PARP inhibitor compounds, compositions and methods of use | Eisai Inc. (US) | 2015-03-04 | — | — | EP | disclosed |
| EP-2590026-A1 | Colored resin powder and toner using the colored resin powder | Canon Kabushiki Kaisha (JP) | 2013-05-08 | — | — | EP | disclosed |
| EP-2094692-B1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1 AND/OR NF-KAPPAB ACTIVITY AND USE THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2012-11-28 | — | — | EP | disclosed |