Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | HPGD | P15428 | 8/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209215 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL10561406 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL15078645 | 0.80 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL21431433 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL13105216 | 0.78 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL174140 | 0.78 | RAB9A (0.65) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL23163298 | 0.77 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL175042 | 0.76 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL212851 | 0.76 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL15077183 | 0.76 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103188936-B | Insecticidal composition | DOW AGROSCIENCES LLC (US) | 2016-04-20 | — | — | CN | disclosed |
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| US-8604211-B2 | Pesticidal compositions | Dow AroSciecnes, LLC. (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2611299-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| CN-103188936-A | Insecticidal composition | DOW AGROSCIENCES LLC | 2013-07-03 | — | — | CN | disclosed |
| WO-2012030681-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | KDM4E 2988/4885ALDH1A1 1882/4885HPGD 1548/4885 |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | KDM4E 2511/4885ALDH1A1 1438/4885HPGD 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.