Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL28141196 | 0.93 | NPC1 (0.49) | TDP1KMT2ASLC6A2SLC6A3NPC1 | |
| SCHEMBL27622766 | 0.88 | LMNA (0.60) | KMT2ANPC1RAB9ATSHRMAPT | |
| SCHEMBL9650496 | 0.88 | MAPT (0.62) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9650487 | 0.88 | L3MBTL1 (0.55) | KMT2ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL10901370 | 0.88 | L3MBTL1 (0.59) | TDP1KMT2ASLC6A2SLC6A3NPC1 | |
| SCHEMBL1630447 | 0.86 | NR4A1 (0.68) | SLC6A2SLC6A3NPC1RAB9AMAPT | |
| SCHEMBL864716 | 0.85 | MAPT (0.61) | TDP1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL9653413 | 0.85 | NPC1 (0.65) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL4689393 | 0.85 | RAB9A (0.56) | TDP1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4888739 | 0.84 | GRM5 (0.54) | KMT2ANPC1RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663256-A | Process for producing optically active cyanohydrin derivative | AGENCY SCIENCE TECH & RES | 2010-03-03 | — | — | CN | claimed |
| CN-101248057-A | Preparation of (+) -catechin, (-) -epicatechin, (-) -catechin, (+) -epicatechin, and their 5, 7, 3 ', 4' -tetra-O-benzyl analogues | MARS INC (US) | 2008-08-20 | — | — | CN | claimed |
| CN-1816328-A | Therapeutic agent | TAKARA BIO INC (JP) | 2006-08-09 | — | — | CN | claimed |
| JP-62145017-A | — | — | None | — | — | JP | disclosed |
| CN-115677667-A | Bifunctional chimera heterocyclic compound and application thereof as androgen receptor degrading agent | 海创药业股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-10934283-B2 | COMT inhibiting methods and compositions | LIEBER INSTITUTE, INC. (US) | 2021-03-02 | — | — | US | disclosed |
| CN-109232251-A | 3, 4-Dihydroxyacetophenone derivative, preparation method, application and pharmaceutical composition | 潍坊医学院 | 2019-01-18 | — | — | CN | disclosed |
| US-20180305354-A1 | COMT Inhibiting Methods and Compositions | LIEBER INSTITUTE, INC. | 2018-10-25 | — | — | US | disclosed |
| CN-108503554-A | A kind of synthetic method of bricalin | 南京倍特医药科技有限公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-105801411-A | Synthesis method of 2-arylformyl-1-arylethanone derivative | 浙江工业大学 | 2016-07-27 | — | — | CN | disclosed |
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | disclosed |
| EP-0311385-A2 | Optically active hydroxybenzylamine derivative, optically active amine-boron compound containing said derivative, and process for producing optically active compound by using said compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-04-12 | — | — | EP | disclosed |
| EP-0292699-A2 | Urea based lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1988-11-30 | — | — | EP | disclosed |
| JP-S62145017-A | ANTIBACTERIAL AGENT | MITSUBISHI CHEM IND LTD | 1987-06-29 | — | — | JP | disclosed |
| US-4490392-A | Benzylalcohol derivative and process for preparing | TANABE SEIYAKU CO., LTD. (JP) | 1984-12-25 | — | — | US | disclosed |
| US-4276304-A | ANTIDIABETIC, ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1981-06-30 | — | — | US | disclosed |
| US-4218479-A | Novel benzylalcohols and pharmaceutical compositions and use thereof | TANABE SEIYAKU CO., LTD. (JP) | 1980-08-19 | — | — | US | disclosed |
| US-4072759-A | Novel benzylalcohol derivatives as antidiabetics and cardiotonics | TANABE SEIYAKU CO., LTD. (JA) | 1978-02-07 | — | — | US | disclosed |
| US-4038412-A | ANTI-VIRAL AGENTS | RICHARDSON-MERRELL INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-4032575-A | BENZYLALCOHOL AMINE DERIVATIVES | TANABE SEIYAKU CO., LTD. (JA) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305354-A1 | COMT Inhibiting Methods and Compositions | COMT, MAOB, MAOA | TDP1 439/4885KMT2A 618/4885SLC6A2 23/4885 |
| US-10934283-B2 | COMT inhibiting methods and compositions | COMT, MAOB, MAOA | TDP1 439/4885KMT2A 618/4885SLC6A2 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.