Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665032 | 0.91 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL359 | 0.91 | GP6 (0.63) | AGTR1AGTR2 | |
| SCHEMBL1257850 | 0.91 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL1257852 | 0.91 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL625 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL626 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL1033 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL1035 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL1034 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL462 | 0.85 | AGTR2 (0.80) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146963-B1 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS | THERAVANCE BIOPHARMA R & D IP LLC (US) | 2014-12-17 | — | — | EP | disclosed |