Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.63 |
| ▸ | AR | P10275 | 6/20 | 0.62 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1630935 | 0.94 | PGR (0.63) | PGRNR3C1NR3C2ARRAB9A | |
| SCHEMBL1631280 | 0.84 | PGR (0.61) | PGRNR3C1NR3C2ARKIF11 | |
| SCHEMBL1631242 | 0.81 | PGR (0.60) | PGRNR3C1NR3C2ARALDH1A1 | |
| SCHEMBL1633786 | 0.81 | PGR (0.68) | PGRNR3C1NR3C2ARKIF11 | |
| SCHEMBL1630826 | 0.80 | PGR (0.74) | PGRNR3C1NR3C2ARALDH1A1 | |
| SCHEMBL1631048 | 0.80 | PGR (0.74) | PGRNR3C1NR3C2ARKIF11 | |
| SCHEMBL1631091 | 0.80 | PGR (0.73) | PGRNR3C1NR3C2ARHPGD | |
| SCHEMBL1630908 | 0.80 | PGR (0.67) | PGRNR3C1NR3C2ARSMN1; SMN2 | |
| SCHEMBL1630736 | 0.79 | PGR (0.63) | PGRNR3C1NR3C2ARALDH1A1 | |
| SCHEMBL1630938 | 0.79 | PGR (0.74) | PGRNR3C1NR3C2ARKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932284-B2 | Indole sulfonamide modulators of progesterone receptors | ELI LILLY AND COMPANY (US) | 2011-04-26 | — | — | US | disclosed |