Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14868088 | 0.89 | MGLL (0.47) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL406705 | 0.87 | MGLL (0.50) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL17170573 | 0.86 | MGLL (0.52) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL14868093 | 0.86 | MGLL (0.52) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL14868091 | 0.86 | MGLL (0.52) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL3482800 | 0.86 | MGLL (0.54) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL14868092 | 0.82 | MGLL (0.44) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL17190596 | 0.79 | MGLL (0.56) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL12056284 | 0.78 | MGLL (0.50) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL19105008 | 0.77 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9862682-B2 | Functionalized pegylated cyanine compounds, pharmaceutical compositions, and methods of use thereof | BroadPharm (US) | 2018-01-09 | — | — | US | disclosed |
| US-20170197916-A1 | FUNCTIONALIZED PEGYLATED CYANINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | BroadPharm (US) | 2017-07-13 | — | — | US | disclosed |
| US-9579367-B2 | C-terminally tethered amino acids and their fibrinolytic therapeutic uses | CANADIAN BLOOD SERVICES (CA) | 2017-02-28 | — | — | US | disclosed |
| US-20140369992-A1 | C-Terminally Tethered Amino Acids and Their Fibrinolytic Therapeutic Uses | CANADIAN BLOOD SERVICES (CA) | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197916-A1 | FUNCTIONALIZED PEGYLATED CYANINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | ABL1, EGFR, ALB | MGLL 1481/4885FAAH 3047/4885ALDH1A1 1441/4885 |
| US-20140369992-A1 | C-Terminally Tethered Amino Acids and Their Fibrinolytic Therapeutic Uses | HABP2, FGB, PROC | MGLL 2673/4885FAAH 1386/4885ALDH1A1 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.