Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 8/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627734 | 0.81 | TSHR (0.58) | TSHRALDH1A1ACHETHRBEPHX1 | |
| SCHEMBL5174474 | 0.79 | ALDH1A1 (0.56) | TSHRALDH1A1ACHETHRBCHRNB2 | |
| SCHEMBL14340134 | 0.79 | TSHR (0.56) | TSHRALDH1A1ACHETHRBEPHX1 | |
| SCHEMBL8596323 | 0.77 | TSHR (0.46) | TSHRALDH1A1ACHETHRBSMN1; SMN2 | |
| SCHEMBL15082337 | 0.77 | ALDH1A1 (0.54) | TSHRALDH1A1ACHETHRBCHRNB2 | |
| SCHEMBL13038105 | 0.77 | SMN1; SMN2 (0.35) | TSHRCHRNB2CHRNA4SMN1; SMN2CHRNB4 | |
| SCHEMBL6318061 | 0.76 | TSHR (0.52) | TSHRALDH1A1ACHETHRBCHRNB2 | |
| SCHEMBL14904496 | 0.76 | ACHE (0.62) | TSHRALDH1A1ACHECHRNB2CHRNA4 | |
| SCHEMBL2818726 | 0.74 | ALDH1A1 (0.60) | TSHRALDH1A1ACHETHRBEPHX1 | |
| SCHEMBL25753021 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8911967-B2 | One pot desialylation and glycopegylation of therapeutic peptides | NOVO NORDISK A/S (DK) | 2014-12-16 | — | — | US | disclosed |