SCHEMBL13627734

SCHEMBL13627734

CCOCCOC(=O)NC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
ALDH1A1 P00352 2/20 0.58
EPHX1 P07099 1/20 0.55
CHRNB2 P17787 2/20 0.52
CHRNA4 P43681 2/20 0.52
CHRM2 P08172 1/20 0.52
CHRM4 P08173 1/20 0.52
CHRM5 P08912 1/20 0.52
CYP2D6 P10635 1/20 0.52
CHRM1 P11229 1/20 0.52
NFKB1 P19838 1/20 0.52
CHRM3 P20309 1/20 0.52
MAPK1 P28482 1/20 0.52
CHRNA7 P36544 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
LMNA P02545 1/20 0.50
APEX1 P27695 1/20 0.50
THRB P10828 1/20 0.50
ACHE P22303 4/20 0.42
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14340134 0.98 TSHR (0.56) TSHRALDH1A1EPHX1CHRNB2CHRNA4
SCHEMBL8403603 0.88 CHRNB2 (0.58) TSHRALDH1A1EPHX1CHRNB2CHRNA4
SCHEMBL10815020 0.88 CHRNB2 (0.58) TSHRALDH1A1EPHX1CHRNB2CHRNA4
SCHEMBL15359193 0.87 EPHX1 (0.62) TSHRALDH1A1EPHX1CHRNB2CHRNA4
SCHEMBL16541245 0.85 CHRNB2 (0.65) EPHX1CHRNB2CHRNA4CHRM2CHRM4
SCHEMBL16342091 0.84 EPHX1 (0.59) TSHRALDH1A1EPHX1CHRNB2CHRNA4
SCHEMBL18776185 0.84 EPHX1 (0.59) TSHRALDH1A1EPHX1CHRNB2CHRNA4
SCHEMBL2818726 0.84 ALDH1A1 (0.60) TSHRALDH1A1EPHX1SMN1; SMN2LMNA
SCHEMBL16307754 0.81 TSHR (0.47) TSHRALDH1A1EPHX1CHRNB2CHRNA4
SCHEMBL24318705 0.80 CHRNB2 (0.50) TSHRALDH1A1EPHX1CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111349185-B Solid catalyst for propylene polymerization and method for producing block copolymer using the same 韩华道达尔能源有限公司 2023-02-03 CN disclosed
US-11427657-B2 Solid catalyst for propylene polymerization and method of producing block copolymer using the same HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2022-08-30 US disclosed
EP-3731869-A1 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2020-11-04 EP disclosed
CN-111349185-A Solid catalyst for propylene polymerization and method for producing block copolymer using the same 韩华道达尔有限公司 2020-06-30 CN disclosed
US-20200199266-A1 Solid Catalyst For Propylene Polymerization And Method Of Producing Block Copolymer Using The Same HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2020-06-25 US disclosed
EP-3670546-A1 SOLID CATALYST FOR PROPYLENE POLYMERIZATION AND METHOD OF PRODUCING BLOCK COPOLYMER USING THE SAME Hanwha Total Petrochemical Co., Ltd. (KR) 2020-06-24 EP disclosed
US-7619092-B2 Piperidine compounds MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-11-17 US disclosed
EP-1383824-B9 COMPOSITE MATERIALS MADE FROM TREATED CELLULOSE AND PLASTIC CYCLETEC LTD (IL) 2009-08-12 EP disclosed
EP-1383824-B1 COMPOSITE MATERIALS MADE FROM TREATED CELLULOSE AND PLASTIC CYCLETEC LTD (IL) 2008-10-29 EP disclosed