SCHEMBL1630809

SCHEMBL1630809

C=CC(=O)OCCCCc1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 10/20 0.50
TSHR P16473 4/20 0.46
HPGD P15428 1/20 0.46
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 1/20 0.46
THRA P10827 6/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.41
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
NAAA Q02083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23937021 0.99 THRB (0.49) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL23937050 0.99 THRB (0.49) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL26268488 0.97 THRB (0.48) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL2311466 0.96 THRB (0.47) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL13839894 0.96 THRB (0.48) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL1628452 0.96 THRB (0.48) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL26268121 0.95 THRB (0.46) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL2307644 0.95 THRB (0.46) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL24263854 0.93 THRB (0.50) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL5032103 0.92 THRB (0.45) THRBTSHRHPGDALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230143174-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE EACH INCLUDING THE ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2023-05-11 US disclosed
US-8835084-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2014-09-16 US disclosed
US-20120087695-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-04-12 US disclosed