Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15424356 | 1.00 | SLC1A2 (0.43) | SLC1A2SLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL31688857 | 0.88 | GSR (0.43) | SLC1A2SLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL31073994 | 0.86 | GRM8 (0.50) | SLC1A2SLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL31074008 | 0.86 | GRM8 (0.50) | SLC1A2SLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL24788159 | 0.86 | OTC (0.40) | SLC1A2SLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL27119962 | 0.85 | GLP1R (0.53) | PTGS1GSTK1NOD1 | |
| SCHEMBL29336452 | 0.85 | DDAH1 (0.43) | SLC1A2SLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL30202320 | 0.85 | DDAH1 (0.43) | SLC1A2SLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL21316673 | 0.85 | GLP1R (0.48) | SLC1A2SLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL31370639 | 0.85 | DDAH1 (0.43) | SLC1A2SLC1A1GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008945-A1 | Novel Insulin Derivatives and the Medical Uses Hereof | NOVO NORDISK A/S (DK) | 2017-01-12 | — | — | US | disclosed |
| EP-2190873-B1 | TRUNCATED GLP-1 DERIVATIVES AND THEIR THERAPEUTICAL USE | NOVO NORDISK AS (DK) | 2015-07-22 | — | — | EP | disclosed |
| EP-2190460-B1 | PEPTIDES DERIVATIZED WITH A-B-C-D- AND THEIR THERAPEUTICAL USE | NOVO NORDISK AS (DK) | 2014-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008945-A1 | Novel Insulin Derivatives and the Medical Uses Hereof | IAPP, INSR, GPR119 | SLC1A2 3859/4885SLC1A1 2708/4885GRM8 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.