Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.68 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 8/20 | 0.53 |
| ▸ | FAAH | O00519 | 5/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23013174 | 0.82 | CACNA1I (0.69) | SIGMAR1CACNA1IHDAC3HDAC4HDAC1 | |
| SCHEMBL1475020 | 0.76 | SIGMAR1 (0.70) | SIGMAR1 | |
| SCHEMBL17517685 | 0.76 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL82572 | 0.75 | ACHE (0.65) | SIGMAR1ACHEBCHE | |
| SCHEMBL4783764 | 0.74 | KCNH2 (0.47) | SIGMAR1CACNA1IHDAC3HDAC4HDAC1 | |
| SCHEMBL14189662 | 0.74 | HDAC3 (0.72) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8395513 | 0.74 | NPC1 (0.66) | HDAC8HDAC6 | |
| SCHEMBL8396806 | 0.74 | NPC1 (0.70) | — | |
| SCHEMBL29508424 | 0.74 | CACNA1I (0.61) | SIGMAR1CACNA1IACHECXCR4GSK3B | |
| SCHEMBL23013177 | 0.74 | CACNA1I (0.61) | SIGMAR1CACNA1IACHECXCR4GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942392-B1 | DIFFERENTIATION OF PLURIPOTENT STEM CELLS | JANSSEN BIOTECH INC (US) | 2018-10-03 | — | — | EP | claimed |
| EP-2942392-A1 | DIFFERENTIATION OF PLURIPOTENT STEM CELLS | Janssen Biotech, Inc. (US) | 2015-11-11 | — | — | EP | claimed |
| EP-2310492-B1 | DIFFERENTIATION OF PLURIPOTENT STEM CELLS | JANSSEN BIOTECH INC (US) | 2015-07-22 | — | — | EP | claimed |
| EP-2853589-A1 | Differentiation of human embryonic stem cells | Janssen Biotech, Inc. (US) | 2015-04-01 | — | — | EP | claimed |
| EP-2611910-A2 | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS | Janssen Biotech, Inc. (US) | 2013-07-10 | — | — | EP | claimed |
| EP-2611909-A2 | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS | Janssen Biotech, Inc. (US) | 2013-07-10 | — | — | EP | claimed |
| WO-2012030538-A2 | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS | JANSSEN BIOTECH, INC. (US) | 2012-03-08 | — | — | WO | claimed |
| WO-2012030539-A2 | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS | JANSSEN BIOTECH, INC. (US) | 2012-03-08 | — | — | WO | claimed |
| US-20120052571-A1 | Differentiation of Human Embryonic Stem Cells | JANSSEN BIOTECH, INC. (US) | 2012-03-01 | — | — | US | claimed |
| US-20120052575-A1 | Differentiation of Human Embryonic Stem Cells | JANSSEN BIOTECH, INC. (US) | 2012-03-01 | — | — | US | claimed |
| US-10351820-B2 | Methods for making definitive endoderm using at least GDF-8 | JANSSEN BIOTECH, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-10351820-B2 | Methods for making definitive endoderm using at least GDF-8 | JANSSEN BIOTECH, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-10233421-B2 | Differentiation of pluripotent stem cells | JANSSEN BIOTECH, INC. (US) | 2019-03-19 | — | — | US | disclosed |
| US-10233421-B2 | Differentiation of pluripotent stem cells | JANSSEN BIOTECH, INC. (US) | 2019-03-19 | — | — | US | disclosed |
| EP-2942392-B1 | DIFFERENTIATION OF PLURIPOTENT STEM CELLS | JANSSEN BIOTECH INC (US) | 2018-10-03 | — | — | EP | disclosed |
| US-20100015711-A1 | Differentiation of Pluripotent Stem Cells | JANSSEN BIOTECH, INC. | 2010-01-21 | — | — | US | disclosed |
| US-20100015711-A1 | Differentiation of Pluripotent Stem Cells | JANSSEN BIOTECH, INC. | 2010-01-21 | — | — | US | disclosed |
| US-20100015711-A1 | Differentiation of Pluripotent Stem Cells | JANSSEN BIOTECH, INC. | 2010-01-21 | — | — | US | disclosed |
| WO-2010002846-A1 | DIFFERENTIATION OF PLURIPOTENT STEM CELLS | CENTOCOR ORTHO BIOTECH INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010002846-A1 | DIFFERENTIATION OF PLURIPOTENT STEM CELLS | CENTOCOR ORTHO BIOTECH INC. (US) | 2010-01-07 | — | — | WO | disclosed |