Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012935 | 0.84 | SIGMAR1 (0.56) | CACNA1ISIGMAR1KDM4ECXCR4HDAC3 | |
| SCHEMBL23013177 | 0.83 | CACNA1I (0.61) | CACNA1ISIGMAR1HTR4CHRM4KDM4E | |
| SCHEMBL29508424 | 0.83 | CACNA1I (0.61) | CACNA1ISIGMAR1HTR4CHRM4KDM4E | |
| SCHEMBL163098 | 0.82 | SIGMAR1 (0.68) | CACNA1ISIGMAR1CXCR4HDAC3HDAC4 | |
| SCHEMBL8146918 | 0.80 | CHRM4 (0.63) | CACNA1ISIGMAR1CHRM4ACHE | |
| SCHEMBL18865857 | 0.80 | HRH3 (0.52) | CACNA1ICHRNB2CHRNA4 | |
| SCHEMBL5773896 | 0.80 | VNN1 (0.58) | CACNA1ISIGMAR1HTR4CHRM4KDM4E | |
| SCHEMBL2868175 | 0.79 | SIGMAR1 (0.58) | CACNA1ISIGMAR1HTR4CHRM4KDM4E | |
| SCHEMBL29960939 | 0.78 | CACNA1I (0.66) | CACNA1IHTR4CXCR4HDAC3HDAC4 | |
| SCHEMBL3942388 | 0.78 | ACHE (0.67) | CXCR4HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017849-A1 | ENZYME INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021032934-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-25 | — | — | WO | disclosed |