SCHEMBL16312908

SCHEMBL16312908

CSc1c(S)c(Cl)cc(Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
HPGD P15428 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CASP1 P29466 1/20 0.33
MAPK1 P28482 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16312913 0.78 CYP3A4 (0.43) CYP3A4HPGDTSHRHSD17B10CASP1
SCHEMBL6520758 0.69 CYP3A4 (0.59) CYP3A4HPGDTSHRHSD17B10CASP1
SCHEMBL9357749 0.69 CYP3A4 (0.50) CYP3A4HPGDTSHRHSD17B10CASP1
SCHEMBL9387769 0.69 CYP3A4 (0.50) CYP3A4HPGDTSHRHSD17B10CASP1
SCHEMBL48326 0.68 CYP3A4 (0.56) CYP3A4HPGDTSHRHSD17B10CASP1
SCHEMBL6512992 0.67 CYP3A4 (0.56) CYP3A4HPGDTSHRHSD17B10CASP1
SCHEMBL6512985 0.67 CYP3A4 (0.56) CYP3A4HPGDTSHRHSD17B10CASP1
SCHEMBL27993900 0.67 CYP3A4 (0.47) CYP3A4HPGDTSHRHSD17B10CASP1
SCHEMBL6511604 0.67 CYP3A4 (0.56) CYP3A4HPGDTSHRHSD17B10CASP1
SCHEMBL260696 0.66 CYP3A4 (0.53) CYP3A4HPGDTSHRHSD17B10CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1496375-B1 Composition for optical film comprising a near-infrared absorbing dye and a quencher ASAHI GLASS CO LTD (JP) 2008-10-15 EP disclosed