SCHEMBL16315752

SCHEMBL16315752

CCCOCCC(=O)NCCO

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.47
CNR1 P21554 6/20 0.45
ALDH1A1 P00352 4/20 0.45
CNR2 P34972 3/20 0.45
MEN1 O00255 2/20 0.45
BLM P54132 2/20 0.45
KMT2A Q03164 2/20 0.45
TRPV1 Q8NER1 2/20 0.45
SELP P16109 1/20 0.45
TRPM8 Q7Z2W7 1/20 0.45
FAAH O00519 1/20 0.45
KCNK3 O14649 1/20 0.45
HPGD P15428 2/20 0.44
MAPT P10636 1/20 0.44
ALOX12 P18054 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2124347 0.88 CASP2 (0.44) NAAACNR1ALDH1A1MEN1KMT2A
SCHEMBL16560390 0.88 EPHX2 (0.45) NAAACNR1MEN1KMT2AFAAH
SCHEMBL25516099 0.86 CASP2 (0.42) NAAACNR1MEN1KMT2AFAAH
SCHEMBL5836462 0.86 CNR1 (0.46) NAAACNR1ALDH1A1CNR2MEN1
SCHEMBL25516101 0.86 CASP2 (0.42) NAAACNR1MEN1KMT2AFAAH
SCHEMBL24982767 0.86 MEN1 (0.46) NAAACNR1MEN1KMT2AFAAH
SCHEMBL19544544 0.86 MEN1 (0.46) NAAACNR1MEN1KMT2AFAAH
SCHEMBL25415126 0.86 NAAA (0.59) NAAACNR1ALDH1A1CNR2MEN1
SCHEMBL5165598 0.86 NAAA (0.59) NAAACNR1ALDH1A1CNR2MEN1
SCHEMBL17874807 0.85 NAAA (0.56) NAAACNR1ALDH1A1CNR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321048-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS MERSANA THERAPEUTICS, INC. 2023-10-12 US disclosed
US-20230172910-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS MERSANA THERAPEUTICS, INC. 2023-06-08 US disclosed
US-20110172390-A1 Protein-Proteophore Complexes ASCENDIS PHARMA A/S (DK) 2011-07-14 US disclosed
US-20070020224-A1 Protein-proteophore complexes ASCENDIS PHARMA GMBH (DE) 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172390-A1 Protein-Proteophore Complexes PSMG3, PSME1, PSMD11 NAAA 1854/4885CNR1 4663/4885ALDH1A1 4508/4885
US-20070020224-A1 Protein-proteophore complexes PSMG3, PSME1, PSMD11 NAAA 1854/4885CNR1 4663/4885ALDH1A1 4508/4885
US-20230321048-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS STING1, CGAS, IFNAR1 NAAA 1904/4885CNR1 2247/4885ALDH1A1 2462/4885
US-20230172910-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS STING1, CGAS, IFNAR1 NAAA 1904/4885CNR1 2247/4885ALDH1A1 2462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.