Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658401 | 0.87 | LPAR3 (0.51) | LPAR3LPAR2LPAR1ENPP2 | |
| SCHEMBL5597304 | 0.83 | LPAR3 (0.47) | LPAR3LPAR2LPAR1ENPP2 | |
| SCHEMBL29048047 | 0.82 | LPAR3 (0.59) | LPAR3LPAR2LPAR1TSHRENPP2 | |
| SCHEMBL27984755 | 0.81 | BTN3A1 (0.42) | LPAR3LPAR2LPAR1BTN3A1ALDH1A1 | |
| SCHEMBL14678815 | 0.81 | ALDH1A1 (0.41) | LPAR3LPAR2LPAR1ALDH1A1TSHR | |
| SCHEMBL1831267 | 0.81 | THRB (0.39) | LPAR3LPAR2LPAR1ALDH1A1TSHR | |
| SCHEMBL28558856 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBMAPT | |
| SCHEMBL5595272 | 0.80 | THRB (0.38) | LPAR3LPAR2LPAR1ALDH1A1TSHR | |
| SCHEMBL1831246 | 0.80 | THRB (0.38) | LPAR3LPAR2LPAR1ALDH1A1TSHR | |
| SCHEMBL29273924 | 0.80 | ALDH1A1 (0.40) | LPAR3LPAR2LPAR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11246572-A | — | — | None | — | — | JP | disclosed |
| US-8883877-B2 | Materials based on radically polymerizable N,O-functionalized acrylic acid hydroxamides | IVOCLAR VIVADENT AG (LI) | 2014-11-11 | — | — | US | disclosed |
| US-20110130486-A1 | Materials Based on Radically Polymerizable N,O-Functionalized Acrylic Acid Hydroxamides | IVOCLAR VIVADENT AG (LI) | 2011-06-02 | — | — | US | disclosed |
| US-7932303-B2 | Materials based on radically polymerizable N,O-functionalized acrylic acid hydroxamides | IVOCLAR VIVADENT AG (LI) | 2011-04-26 | — | — | US | disclosed |
| US-20080234405-A1 | very quickly cured; particularly suitable for dental purposes | IVOCLAR VIVADENT AG (LI) | 2008-09-25 | — | — | US | disclosed |
| US-6953832-B2 | Dental materials based on polyfunctional amides | IVOCLAR VIVADENT AG (LI) | 2005-10-11 | — | — | US | disclosed |
| US-20020143138-A1 | For use as dental adhesive, coating material, filling material or dental cement | IVOCLAR VIVADENT AG (LI) | 2002-10-03 | — | — | US | disclosed |
| US-6172131-B1 | MADE BY REACTING AN ALPHA-HALOMETHACRYLIC ACID ESTER WITH PROTECTED MONO- OR DIFUNCTIONAL PHOSPHONIC ACID ESTERS; USE AS COMPONENT OF DENTAL ADHESIVES DUE TO THEIR ADHESION-PROMOTING PROPERTIES | IVOCLAR AG | 2001-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130486-A1 | Materials Based on Radically Polymerizable N,O-Functionalized Acrylic Acid Hydroxamides | H1-0, H1-2, H1-3 | LPAR3 2872/4885LPAR2 2729/4885LPAR1 2985/4885 |
| US-20080234405-A1 | very quickly cured; particularly suitable for dental purposes | HRH4, HRH2, HRH3 | LPAR3 2301/4885LPAR2 2831/4885LPAR1 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.