Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595272 | 1.00 | THRB (0.38) | THRBLPAR3LPAR2LPAR1TSHR | |
| SCHEMBL1831267 | 0.98 | THRB (0.39) | THRBLPAR3LPAR2LPAR1TSHR | |
| SCHEMBL6474037 | 0.91 | THRB (0.38) | THRBTSHRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL5595161 | 0.89 | LPAR3 (0.42) | THRBLPAR3LPAR2LPAR1TSHR | |
| SCHEMBL9906105 | 0.89 | THRB (0.39) | THRBTSHRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1831610 | 0.88 | LPAR3 (0.49) | LPAR3LPAR2LPAR1TSHR | |
| Phosphoric Acid SCHEMBL5595983 | 0.87 | THRB (0.47) | THRBTSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL12297123 | 0.87 | THRB (0.47) | THRBTSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL23894805 | 0.85 | THRB (0.48) | THRBTSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL12394924 | 0.84 | TPI1 (0.35) | LPAR3LPAR2LPAR1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601679-B1 | A POYMERIZABLE PHOSPHORIC ACID ESTER DERIVATIVE AND A DENTAL COMPOSITION EMPLOYING IT. | DENTSPLY DETREY GMBH (DE) | 2011-05-11 | — | — | EP | disclosed |
| US-20060246017-A1 | Polymerizable phosphoric acid ester derivative and a dental composition employing it | DENTSPLY DE TREY GMBH (DE) | 2006-11-02 | — | — | US | disclosed |
| EP-1601679-A2 | A POYMERIZABLE PHOSPHORIC ACID ESTER DERIVATIVE AND A DENTAL COMPOSITION EMPLOYING IT. | DENTSPLY DETREY GmbH (DE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004078100-A2 | A POYMERIZABLE PHOSPHORIC ACID ESTER DERIVATIVE AND A DENTAL COMPOSITION EMPLOYING IT. | DENTSPLY DE TREY GMBH (DE) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060246017-A1 | Polymerizable phosphoric acid ester derivative and a dental composition employing it | CBR1, HCAR1, OXSR1 | THRB 1723/4885LPAR3 877/4885LPAR2 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.