SCHEMBL16319109

SCHEMBL16319109

CNC(=O)C(=NOC)C(C)=CCOc1ccn(-c2ccc(Cl)c(C(F)(F)F)c2)n1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 6/20 0.41
SIGMAR1 Q99720 8/20 0.37
KCNH2 Q12809 2/20 0.37
MET P08581 1/20 0.36
KIT P10721 1/20 0.36
KDR P35968 1/20 0.36
FLT3 P36888 1/20 0.36
AR P10275 1/20 0.34
GPR119 Q8TDV5 1/20 0.33
BRAF P15056 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16319106 1.00 NOTUM (0.41) NOTUMSIGMAR1KCNH2METKIT
SCHEMBL16319107 1.00 NOTUM (0.41) NOTUMSIGMAR1KCNH2METKIT
SCHEMBL16319188 0.90 SIGMAR1 (0.46) NOTUMSIGMAR1KCNH2
SCHEMBL16319190 0.90 SIGMAR1 (0.46) NOTUMSIGMAR1KCNH2
SCHEMBL16319191 0.90 SIGMAR1 (0.46) NOTUMSIGMAR1KCNH2
SCHEMBL16319282 0.89 SIGMAR1 (0.39) NOTUMSIGMAR1KCNH2MET
SCHEMBL16319286 0.89 SIGMAR1 (0.39) NOTUMSIGMAR1KCNH2MET
SCHEMBL16319284 0.89 SIGMAR1 (0.39) NOTUMSIGMAR1KCNH2MET
SCHEMBL16319174 0.87 SIGMAR1 (0.39) SIGMAR1KCNH2
SCHEMBL16319177 0.87 SIGMAR1 (0.39) SIGMAR1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2019-04-04 US claimed
US-20180235221-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2018-08-23 US claimed
EP-3267797-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2018-01-17 EP claimed
EP-3010344-B1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2017-11-15 EP claimed
US-9763448-B2 Fungicidal mixtures I comprising strobilurin-type fungicides BASF SE (DE) 2017-09-19 US claimed
WO-2016142224-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2016-09-15 WO claimed
EP-2815650-B1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2016-08-17 EP claimed
US-20160135459-A1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF Agro B.V. (NL) 2016-05-19 US claimed
EP-3010344-A1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2016-04-27 EP claimed
EP-2835052-A1 Fungicidal mixtures comprising pyrimidine fungicides BASF SE (DE) 2015-02-11 EP claimed
EP-2815650-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP claimed
EP-2815649-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP claimed
WO-2014202421-A1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2014-12-24 WO claimed
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2019-04-04 US disclosed
US-20180235221-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2018-08-23 US disclosed
EP-3267797-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2018-01-17 EP disclosed
EP-2835052-A1 Fungicidal mixtures comprising pyrimidine fungicides BASF SE (DE) 2015-02-11 EP disclosed
EP-2815650-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP disclosed
WO-2014202421-A1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2014-12-24 WO disclosed
EP-2815649-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180235221-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES DDT, STS, SNX1 NOTUM 431/4885SIGMAR1 3797/4885KCNH2 803/4885
US-20160135459-A1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES STS, SNX1, SFXN1 NOTUM 592/4885SIGMAR1 3281/4885KCNH2 1450/4885
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES DDT, SNX3, SFXN3 NOTUM 644/4885SIGMAR1 3647/4885KCNH2 894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.