Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 4/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934516 | 0.86 | NPY2R (0.46) | NPY2RCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL518633 | 0.78 | CYP2C9 (0.53) | CYP2C9CYP2C19HTR2BMAPK14SCD | |
| SCHEMBL25933 | 0.76 | POLB (0.58) | NPY2RCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL3402775 | 0.76 | ELANE (0.35) | — | |
| SCHEMBL27728713 | 0.74 | SCD (0.51) | NPY2RCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL1921758 | 0.74 | CYP2C9 (0.49) | CYP2C9CYP2C19HTR2BMAPK14SCD | |
| SCHEMBL2818668 | 0.71 | SPR (0.45) | NPY2RCYP2C9CYP2C19HTR2BMAPK14 | |
| Trifluoroacetic Acid SCHEMBL518486 | 0.70 | CYP2C9 (0.48) | CYP2C9CYP2C19HTR2BMAPK14SCD | |
| SCHEMBL2863943 | 0.70 | LMNA (0.51) | — | |
| SCHEMBL1222761 | 0.69 | SIGMAR1 (0.55) | NPY2RCYP2C9CYP2C19HTR2BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328898-B1 | 2-HETEROARYL-PYRROLO[3,4-C]PYRROLE DERIVATIVES AND THEIR USE AS SCD INHIBITORS | SANOFI SA (FR) | 2014-12-24 | — | — | EP | disclosed |