Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 16/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319242 | 1.00 | NFE2L2 (0.56) | NFE2L2GRM4RELAKDM4ENPC1 | |
| SCHEMBL7970832 | 0.83 | LOXL2 (0.45) | NFE2L2GRM4NPC1SMN1; SMN2 | |
| SCHEMBL7970830 | 0.83 | LOXL2 (0.45) | NFE2L2GRM4NPC1SMN1; SMN2 | |
| SCHEMBL2879571 | 0.74 | NFE2L2 (0.52) | NFE2L2GRM4 | |
| SCHEMBL20995878 | 0.74 | NFE2L2 (0.67) | NFE2L2RELARAB9A | |
| SCHEMBL2879570 | 0.74 | NFE2L2 (0.52) | NFE2L2GRM4 | |
| SCHEMBL20995876 | 0.74 | NFE2L2 (0.67) | NFE2L2RELARAB9A | |
| SCHEMBL3264395 | 0.74 | NQO2 (0.56) | NPC1RAB9A | |
| SCHEMBL2234105 | 0.74 | NFE2L2 (1.00) | NFE2L2GRM4RELAKDM4ENPC1 | |
| SCHEMBL14401252 | 0.73 | NFE2L2 (1.00) | NFE2L2RELANPC1PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638022-B1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL MYERS SQUIBB CO (US) | 2014-12-24 | — | — | EP | disclosed |