Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.58 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319336 | 0.88 | SCN9A (0.55) | SCN9ASLC22A12SCN5A | |
| SCHEMBL679379 | 0.85 | SCN9A (0.56) | SCN9ASCN5A | |
| SCHEMBL16239723 | 0.84 | SCN9A (0.59) | SCN9ASCN5ANPC1TP53RAB9A | |
| SCHEMBL16319583 | 0.84 | SCN9A (0.74) | SCN9ASCN5A | |
| SCHEMBL16319578 | 0.83 | SCN9A (0.77) | SCN9ASCN5A | |
| SCHEMBL680467 | 0.83 | SCN9A (0.72) | SCN9ASCN5A | |
| SCHEMBL16319775 | 0.82 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL16319559 | 0.82 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL16319835 | 0.82 | SCN9A (0.74) | SCN9ASCN5A | |
| SCHEMBL679781 | 0.81 | SCN9A (0.67) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |