Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | OGG1 | O15527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2374953 | 0.76 | HPGD (0.46) | L3MBTL1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL2053980 | 0.69 | KDM4E (0.46) | KDM4EGAAMAPTHSD17B10IDO1 | |
| SCHEMBL3409550 | 0.68 | KDM4E (0.58) | KDM4EGAAMAPTHSD17B10IDO1 | |
| SCHEMBL16319417 | 0.66 | KDM4E (0.46) | KDM4EGAAMAPTHSD17B10IDO1 | |
| SCHEMBL16320285 | 0.66 | KDM4E (0.42) | KDM4EGAAMAPTHSD17B10IDO1 | |
| SCHEMBL2375290 | 0.66 | KDM4E (0.35) | KDM4EGAAMAPTHSD17B10IDO1 | |
| SCHEMBL16319389 | 0.65 | MAPT (0.45) | KDM4EGAAMAPTIDO1NPC1 | |
| SCHEMBL3108811 | 0.64 | KDM4E (0.58) | KDM4EGAAMAPTHSD17B10CTSK | |
| SCHEMBL28455999 | 0.64 | KDM4E (0.41) | KDM4EGAAMAPTHSD17B10IDO1 | |
| SCHEMBL12616192 | 0.63 | CTSK (0.47) | KDM4EGAAMAPTHSD17B10IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2544684-B1 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-1 (DPP-1) | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-24 | — | — | EP | disclosed |