Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825071 | 0.79 | HSPA5 (0.57) | LMNATTRMEN1KMT2AMAPT | |
| SCHEMBL67463 | 0.78 | CYP3A4 (0.62) | LMNATTRMEN1KMT2AMAPT | |
| SCHEMBL16351512 | 0.76 | CYP1A2 (0.45) | LMNATTRMEN1KMT2AMAPT | |
| SCHEMBL16341500 | 0.73 | HSP90AA1 (0.62) | LMNATTRMEN1KMT2AMAPT | |
| SCHEMBL16320620 | 0.69 | HSPA5 (0.45) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL16320314 | 0.68 | KMT2A (0.46) | LMNATTRMEN1KMT2AMAPT | |
| SCHEMBL14616155 | 0.67 | CYP3A4 (0.56) | LMNATTRMEN1KMT2AMAPT | |
| SCHEMBL4814298 | 0.65 | GFER (0.46) | LMNATTRMEN1KMT2AMAPT | |
| SCHEMBL18620124 | 0.65 | APOBEC3G (0.38) | LMNAMEN1KMT2AMAPTPOLB | |
| SCHEMBL2120858 | 0.65 | CYP3A4 (0.59) | LMNATTRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150676-B2 | Thio-salalen catalyst | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-06 | — | — | US | disclosed |
| US-20140378634-A1 | Thio-Salalen Catalyst | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-12-25 | — | — | US | disclosed |
| WO-2014204624-A1 | THIO-SALALEN CATALYST | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378634-A1 | Thio-Salalen Catalyst | TST, SPR, STS | LMNA 4457/4885TTR 517/4885MEN1 3787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.