Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.57 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329673 | 0.91 | SMPD1 (0.56) | LIPEC5AR1ENPP2KMT2AKDM4E | |
| SCHEMBL29956215 | 0.91 | NPC1 (0.57) | LIPEENPP2KMT2AKDM4ENPC1 | |
| SCHEMBL906202 | 0.91 | NPC1 (0.57) | LIPEENPP2KMT2AKDM4ENPC1 | |
| SCHEMBL28606699 | 0.87 | LIPE (0.68) | LIPEC5AR1ENPP2POLBUBE2N | |
| SCHEMBL212034 | 0.85 | LIPE (0.53) | LIPEENPP2NPC1FOLH1 | |
| SCHEMBL544428 | 0.85 | LIPE (0.53) | LIPEENPP2KMT2AMAPTNPC1 | |
| SCHEMBL1163386 | 0.85 | LIPE (0.57) | LIPEC5AR1ENPP2MAPTMAPK1 | |
| SCHEMBL8453 | 0.85 | ENPP2 (0.66) | LIPEENPP2KMT2AMAPTNPC1 | |
| SCHEMBL17236436 | 0.85 | RAB9A (0.56) | LIPEENPP2KDM4EHPGDRAB9A | |
| SCHEMBL29954345 | 0.85 | LIPE (0.53) | LIPEENPP2NPC1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2818531-B1 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| US-9567526-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-02-14 | — | — | US | disclosed |
| EP-2818531-A1 | Polymerisable compounds and the use thereof in liquid-crystal displays | Merck Patent GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| US-20140375943-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-12-25 | — | — | US | disclosed |