Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 14/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16320708 | 0.90 | PDE10A (0.43) | PDE10A | |
| SCHEMBL16340802 | 0.78 | — | — | |
| SCHEMBL16003886 | 0.77 | NOTUM (0.45) | PDE10AMEN1KMT2AGRM5 | |
| SCHEMBL16320445 | 0.74 | PDE10A (0.58) | PDE10A | |
| SCHEMBL16340755 | 0.72 | GPR119 (0.35) | MEN1KMT2APDK2GPR119 | |
| SCHEMBL16340966 | 0.72 | PDE10A (0.43) | PDE10AGRM5 | |
| SCHEMBL16003900 | 0.71 | NPC1 (0.42) | PDE10AGRM5 | |
| SCHEMBL28879588 | 0.70 | PDE10A (0.42) | PDE10AMEN1KMT2AGRM5 | |
| SCHEMBL16320993 | 0.70 | PDE10A (0.47) | PDE10A | |
| Hydrochloric Acid SCHEMBL16341551 | 0.70 | NPC1 (0.41) | PDE10AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378447-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378447-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | PDE10A 1/4885MEN1 4110/4885KMT2A 2932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.